Polyethyleneimine

Polyethyleneimine Structure
Polyethyleneimine structure
Common Name Polyethyleneimine
CAS Number 9002-98-6 Molecular Weight 43.06780
Density 1.030 g/mL at 25 °C Boiling Point 250 °C(lit.)
Molecular Formula C2H5N Melting Point 59-60°C
MSDS Chinese USA Flash Point >230 °F
Symbol GHS07 GHS09
GHS07, GHS09
Signal Word Warning

Loss of INPP4B causes a DNA repair defect through loss of BRCA1, ATM and ATR and can be targeted with PARP inhibitor treatment.

Oncotarget 6 , 10548-62, (2015)

Treatment options for ovarian cancer patients remain limited and overall survival is less than 50% despite recent clinical advances. The lipid phosphatase inositol polyphosphate 4-phosphatase type II (INPP4B) has been described as a tumor suppressor in the PI...