2-Hydrazinylpyridine
2-Hydrazinylpyridine structure
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Common Name | 2-Hydrazinylpyridine | ||
|---|---|---|---|---|
| CAS Number | 4930-98-7 | Molecular Weight | 109.129 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 269.7±0.0 °C at 760 mmHg | |
| Molecular Formula | C5H7N3 | Melting Point | 41-44 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 127.0±19.8 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Steroid hormones in prediction of normal pressure hydrocephalus.
J. Steroid Biochem. Mol. Biol. 152 , 124-32, (2015) Normal pressure hydrocephalus (NPH) is a treatable neurological disorder affecting elderly people with the prevalence increasing with age. NPH is caused by abnormal cerebrospinal fluid (CSF) reabsorption and manifested as a balance impairment, urinary inconti... |
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Simultaneous determination of 17alpha-hydroxypregnenolone and 17alpha-hydroxyprogesterone in dried blood spots from low birth weight infants using LC-MS/MS.
J. Pharm. Biomed. Anal. 48(1) , 177-82, (2008) 17alpha-hydroxypregnenolone (17OHPreg) has heretofore been considered to be the major cause of the false elevated 17alpha-hydroxyprogesterone (17OHP) value in the immunoassay-based newborn screening for congenital adrenal hyperplasia (CAH). To verify this poi... |
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Liquid chromatography-tandem mass spectrometric method for determination of salivary 17alpha-hydroxyprogesterone: a noninvasive tool for evaluating efficacy of hormone replacement therapy in congenital adrenal hyperplasia.
J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 867(1) , 49-56, (2008) A sensitive liquid chromatography-electrospray ionization-tandem mass spectrometric (LC-ESI-MS-MS) method for the quantification of 17alpha-hydroxyprogesterone (17OHP) in human saliva has been developed and validated. The saliva was deproteinized with acetoni... |
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Quantification of 2-hydrazinopyridine derivatized steroid hormones in fathead minnow (Pimephales promelas) blood plasma using LC-ESI+/MS/MS.
J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 879(9-10) , 591-8, (2011) Fathead minnows (Pimephales promelas) comprise a species-of-choice for the hazard assessments of various environmental contaminants, including compounds capable of disrupting endocrine function. Towards this end, the use of liquid chromatography coupled with ... |
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Salivary chenodeoxycholic acid and its glycine-conjugate: their determination method using LC-MS/MS and variation of their concentrations with increased saliva flow rate.
Steroids 75(4-5) , 338-45, (2010) Measurement of steroid levels in saliva has been proposed as a new laboratory tool for characterizing steroid metabolism, but it is not known whether the salivary levels of bile acids can be measured with accuracy and if so, whether such measurements provide ... |
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Structure of human semicarbazide-sensitive amine oxidase/vascular adhesion protein-1.
Acta Crystallogr. D Biol. Crystallogr. 61(Pt 11) , 1550-62, (2005) Semicarbazide-sensitive amine oxidase (SSAO) belongs to a ubiquitous family of copper-containing amine oxidases (CuAOs). SSAO is also known as vascular adhesion protein-1 (VAP-1) and has been identified as one of the adhesion molecules involved in the leukocy... |
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Catalytic mechanism of the quinoenzyme amine oxidase from Escherichia coli: exploring the reductive half-reaction.
Biochemistry 36(7) , 1608-20, (1997) The crystal structure of the complex between the copper amine oxidase from Escherichia coli (ECAO) and a covalently bound inhibitor, 2-hydrazinopyridine, has been determined to a resolution of 2.0 A. The inhibitor covalently binds at the 5 position of the qui... |
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Design and synthesis of a new class of membrane-permeable triazaborolopyridinium fluorescent probes.
J. Am. Chem. Soc. 133(17) , 6780-90, (2011) A new class of fluorescent triazaborolopyridinium compounds was synthesized from hydrazones of 2-hydrazinylpyridine (HPY) and evaluated as potential dyes for live-cell imaging applications. The HPY dyes are small, their absorption/emission properties are tuna... |
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The metal function in the reactions of bovine serum amine oxidase with substrates and hydrazine inhibitors.
J. Biol. Inorg. Chem. 4(3) , 348-53, (1999) Bovine serum amine oxidase (BSAO) reacts with 2-hydrazinopyridine, which binds the organic co-factor 2,4,5-trihydroxyphenylalanine quinone, forming a band at 435 nm. The band shifts to 526 nm around 60 degrees C, to 415 nm upon denaturation, but only shifts t... |
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Studies on the active site of pig plasma amine oxidase.
Biochem. J. 264(3) , 663-9, (1989) Amine oxidase from pig plasma (PPAO) has two bound Cu2+ ions and at least one pyrroloquinoline quinone (PQQ) moiety as cofactors. It is shown that recovery of activity by copper-depleted PPAO is linear with respect to added Cu2+ ions. Recovery of e.s.r. and o... |