N1-Benzyloxycarbonyl-1,3-diaminopropane hydrochloride

N1-Benzyloxycarbonyl-1,3-diaminopropane hydrochloride Structure
N1-Benzyloxycarbonyl-1,3-diaminopropane hydrochloride structure
Common Name N1-Benzyloxycarbonyl-1,3-diaminopropane hydrochloride
CAS Number 17400-34-9 Molecular Weight 244.718
Density 1.109g/cm3 Boiling Point 368.2ºC at 760mmHg
Molecular Formula C11H17ClN2O2 Melting Point 185-189 °C
MSDS USA Flash Point 176.5ºC
Symbol GHS07
GHS07
Signal Word Warning

Nonpeptide renin inhibitors with good intraduodenal bioavailability and efficacy in dog.

J. Med. Chem. 37 , 2991, (1994)

The aim of this study was the discovery of nonpeptide renin inhibitors with much improved oral absorption, bioavailability, and efficacy, for use as antihypertensive agents. Our prior efforts led to the identification of A-74273 [1,R = 3-(4-morpholino)propyl]...

Tri- and tetrapeptide analogues of kinins as potential renal vasodilators.

J. Med. Chem. 27 , 325, (1984)

Tri- and tetrapeptide analogues were synthesized and evaluated as renal vasodilators. These peptides were prepared by standard coupling reactions, which also provided good yields with hindered alpha-methyl amino acid derivatives. Preliminary evidence of renal...