4-Methyl-2-nitrobenzonitrile

4-Methyl-2-nitrobenzonitrile Structure
4-Methyl-2-nitrobenzonitrile structure
Common Name 4-Methyl-2-nitrobenzonitrile
CAS Number 26830-95-5 Molecular Weight 162.145
Density 1.3±0.1 g/cm3 Boiling Point 338.9±30.0 °C at 760 mmHg
Molecular Formula C8H6N2O2 Melting Point 97-99 °C(lit.)
MSDS Chinese USA Flash Point 158.8±24.6 °C
Symbol GHS07
GHS07
Signal Word Warning

Electrostatic fields near the active site of human aldose reductase: 2. New inhibitors and complications caused by hydrogen bonds.

Biochemistry 50(39) , 8311-22, (2011)

Vibrational Stark effect spectroscopy was used to measure electrostatic fields in the hydrophobic region of the active site of human aldose reductase (hALR2). A new nitrile-containing inhibitor was designed and synthesized, and the X-ray structure of its comp...