N6,N6-dimethyladenine
N6,N6-dimethyladenine structure
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Common Name | N6,N6-dimethyladenine | ||
|---|---|---|---|---|
| CAS Number | 938-55-6 | Molecular Weight | 163.180 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 427.4±25.0 °C at 760 mmHg | |
| Molecular Formula | C7H9N5 | Melting Point | 259-262 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 212.3±23.2 °C | |
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Placental development during early pregnancy in sheep: effects of embryo origin on vascularization.
Reproduction 147(5) , 639-48, (2014) Utero-placental growth and vascular development are critical for pregnancy establishment that may be altered by various factors including assisted reproductive technologies (ART), nutrition, or others, leading to compromised pregnancy. We hypothesized that pl... |
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A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases.
Proc. Natl. Acad. Sci. U. S. A. 104 , 20523-8, (2007) Protein kinases play a pivotal role in cell signaling, and dysregulation of many kinases has been linked to disease development. A large number of kinase inhibitors are therefore currently under investigation in clinical trials, and so far seven inhibitors ha... |
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Circadian rhythms. Decoupling circadian clock protein turnover from circadian period determination.
Science 347(6221) , 1257277, (2015) The mechanistic basis of eukaryotic circadian oscillators in model systems as diverse as Neurospora, Drosophila, and mammalian cells is thought to be a transcription-and-translation-based negative feedback loop, wherein progressive and controlled phosphorylat... |
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First polar body morphology affects potential development of porcine parthenogenetic embryo in vitro.
Zygote 23 , 615-21, (2015) Previous studies have reported that the first polar body (PB1) morphology reflects embryo development competence, but the effects of PB1 on porcine embryo development remain unknown. This study aims to determine whether the ability of porcine embryo developme... |
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Cheetah interspecific SCNT followed by embryo aggregation improves in vitro development but not pluripotent gene expression.
Reproduction 150 , 1-10, (2015) The aim of this study was to evaluate the capacity of domestic cat (Dc, Felis silvestris) oocytes to reprogram the nucleus of cheetah (Ch, Acinonyx jubatus) cells by interspecies SCNT (iSCNT), by using embryo aggregation. Dc oocytes were in vitro matured and ... |
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Tiger, Bengal and Domestic Cat Embryos Produced by Homospecific and Interspecific Zona-Free Nuclear Transfer.
Reprod. Domest. Anim. 50 , 849-57, (2015) The aim of this study was to evaluate three different cloning strategies in the domestic cat (Felis silvestris) and to use the most efficient to generate wild felid embryos by interspecific cloning (iSCNT) using Bengal (a hybrid formed by the cross of Felis s... |
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Disruption of exogenous eGFP gene using RNA-guided endonuclease in bovine transgenic somatic cells.
Zygote 23 , 916-23, (2015) Genome-editing technologies are considered to be an important tool for generating gene knockout cattle models. Here, we report highly efficient disruption of a chromosomally integrated eGFP gene in bovine somatic cells using RNA-guided endonucleases, a new cl... |
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In vitro and in vivo developmental competence of dromedary (Camelus dromedarius) oocytes following in vitro fertilization or parthenogenetic activation.
Anim. Reprod. Sci. 113 , 212-9, (2009) Parthenogenetic activation of the oocyte represents an important step in the somatic cloning. The aim of the present study was to evaluate the effectiveness (in term of in vitro development) of different methods of parthenogenetic activation of dromedary oocy... |
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Evidence for conserved DNA and histone H3 methylation reprogramming in mouse, bovine and rabbit zygotes.
Epigenetics Chromatin 1 , 8, (2008) In mammals the parental genomes are epigenetically reprogrammed after fertilization. This reprogramming includes a rapid demethylation of the paternal (sperm-derived) chromosomes prior to DNA replication in zygotes. Such active DNA demethylation in the zygote... |
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Changes of spontaneous parthenogenetic activation and development potential of golden hamster oocytes during the aging process.
Acta Histochem. 117(1) , 104-10, (2015) The golden hamster is an excellent animal experimental model for oocyte research. The hamster oocytes are very useful in clinical examination of human spermatozoan activity. Non-fertile oocytes can lead to time-dependent processes of aging, which will affect ... |