Acetovanillone
Acetovanillone structure
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Common Name | Acetovanillone | ||
|---|---|---|---|---|
| CAS Number | 498-02-2 | Molecular Weight | 166.174 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 297.5±0.0 °C at 760 mmHg | |
| Molecular Formula | C9H10O3 | Melting Point | 112-115 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 125.5±15.8 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Mutual enhancement between high-mobility group box-1 and NADPH oxidase-derived reactive oxygen species mediates diabetes-induced upregulation of retinal apoptotic markers.
J. Physiol. Biochem. 71 , 359-72, (2015) The expression of the proinflammatory cytokine high-mobility group box-1 (HMGB1) is upregulated in epiretinal membranes and vitreous fluid from patients with proliferative diabetic retinopathy (PDR) and in the diabetic retina. We hypothesized that a novel mec... |
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Pigment epithelium-derived factor inhibits retinal microvascular dysfunction induced by 12/15-lipoxygenase-derived eicosanoids.
Biochim. Biophys. Acta 1851(3) , 290-8, (2015) We recently demonstrated that 12/15-lipoxygenase (LOX) derived metabolites, hydroxyeicosatetraenoic acids (HETEs), contribute to diabetic retinopathy (DR) via NADPH oxidase (NOX) and disruption of the balance in retinal levels of the vascular endothelial grow... |
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Carbamazepine attenuates inducible nitric oxide synthase expression through Akt inhibition in activated microglial cells.
Pharm. Biol. 52(11) , 1451-9, (2014) Abstract Background: Carbamazepine, which was developed primarily for the treatment of epilepsy, is now also useful for the treatment of non-epileptic disorders and inflammatory hyperalgesia. However, the mechanism of its anti-neuroinflammatory action remains... |
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Activation of AMP-activated protein kinase protects against homocysteine-induced apoptosis of osteocytic MLO-Y4 cells by regulating the expressions of NADPH oxidase 1 (Nox1) and Nox2.
Bone 77 , 135-41, (2015) Elevated plasma homocysteine (Hcy) level is associated with the risk of osteoporotic fracture. While Hcy increases oxidative stress, AMP-activated protein kinase (AMPK) activation ameliorates it. This study aimed to investigate whether Hcy induces apoptosis o... |
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NADPH oxidase mediated maneb- and paraquat-induced oxidative stress in rat polymorphs: Crosstalk with mitochondrial dysfunction.
Pestic. Biochem. Physiol. 123 , 74-86, (2015) Oxidative stress is a key factor in Parkinson's disease (PD) pathogenesis. Nicotinamide adenine dinucleotide phosphate (NADPH) oxidase and impaired mitochondrion regulate oxidative stress-mediated maneb (MB)- and paraquat (PQ)-induced Parkinsonism. However, t... |
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Ameliorative effect of mepenzolate bromide against pulmonary fibrosis.
J. Pharmacol. Exp. Ther. 350(1) , 79-88, (2014) Idiopathic pulmonary fibrosis is thought to involve lung injury caused by reactive oxygen species (ROS), which in turn is followed by abnormal fibrosis. A transforming growth factor (TGF)-β1-induced increase in myofibroblast number plays an important role in ... |
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Xanthine oxidoreductase regulates macrophage IL1β secretion upon NLRP3 inflammasome activation.
Nat. Commun. 6 , 6555, (2015) Activation of the NLRP3 inflammasome by microbial ligands or tissue damage requires intracellular generation of reactive oxygen species (ROS). We present evidence that macrophage secretion of IL1β upon stimulation with ATP, crystals or LPS is mediated by a ra... |
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Enhancement of neutrophil autophagy by an IVIG preparation against multidrug-resistant bacteria as well as drug-sensitive strains.
J. Leukoc. Biol. 98 , 107-17, (2015) Autophagy occurs in human neutrophils after the phagocytosis of multidrug-resistant bacteria and drug-sensitive strains, including Escherichia coli and Pseudomonas aeruginosa. The present study detected autophagy by immunoblot analysis of LC3B conversion, by ... |
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Diapocynin, a dimer of the NADPH oxidase inhibitor apocynin, reduces ROS production and prevents force loss in eccentrically contracting dystrophic muscle.
PLoS ONE 9(10) , e110708, (2014) Elevation of intracellular Ca2+, excessive ROS production and increased phospholipase A2 activity contribute to the pathology in dystrophin-deficient muscle. Moreover, Ca2+, ROS and phospholipase A2, in particular iPLA2, are thought to potentiate each other i... |
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Endothelial dysfunction impairs vascular neurotransmission in tail arteries.
Neurochem. Int. 80 , 7-13, (2015) The present study intends to clarify if endothelium dysfunction impairs vascular sympathetic neurotransmission. Electrically-evoked tritium overflow (100 pulses/5 Hz) was evaluated in arteries (intact and denuded) or exhibiting some degree of endothelium dysf... |