Tritylthiol

Tritylthiol Structure
Tritylthiol structure
Common Name Tritylthiol
CAS Number 3695-77-0 Molecular Weight 276.395
Density 1.1±0.1 g/cm3 Boiling Point 403.8±14.0 °C at 760 mmHg
Molecular Formula C19H16S Melting Point 104-106 °C(lit.)
MSDS Chinese USA Flash Point 166.5±10.3 °C
Symbol GHS07
GHS07
Signal Word Warning

Structure-activity relationship of S-trityl-L-cysteine analogues as inhibitors of the human mitotic kinesin Eg5.

J. Med. Chem. 51 , 1115-25, (2008)

The human kinesin Eg5 is a potential drug target for cancer chemotherapy. Eg5 specific inhibitors cause cells to block in mitosis with a characteristic monoastral spindle phenotype. Prolonged metaphase block eventually leads to apoptotic cell death. S-trityl-...