Carteolol (hydrochloride)

Carteolol (hydrochloride) Structure
Carteolol (hydrochloride) structure
Common Name Carteolol (hydrochloride)
CAS Number 51781-21-6 Molecular Weight 328.834
Density 1.13g/cm3 Boiling Point 518.6ºC at 760mmHg
Molecular Formula C16H25ClN2O3 Melting Point 278ºC
MSDS N/A Flash Point 267.4ºC

Allergic contact dermatitis due to carteolol, with good tolerance to betaxolol.

Dermatitis 22(4) , 232-3, (2011)

Spectroscopic studies on the interaction of carteolol hydrochloride and urea-induced bovine serum albumin.

Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 113 , 447-51, (2013)

The interaction of carteolol hydrochloride, to 0.2 mol L(-1) urea-induced bovine serum albumin in aqueous solution has been first investigated by fluorescence spectra and ultraviolet-visible (UV-vis) spectra at pH 7.40. The quenching mechanism, binding parame...

Time course of changes in ocular aberrations after instillation of carteolol long-acting solution and timolol gel-forming solution.

J. Ocul. Pharmacol. Ther. 27(2) , 179-85, (2011)

To investigate the influence of 2% carteolol long-acting solution (long-acting carteolol) and 0.5% timolol gel-forming solution (timolol gel) on ocular wavefront aberrations.Ocular aberrations were assessed in the right eye of 24 healthy volunteers at baselin...

Effects of topical carteolol on retinal arterial blood flow in primary open-angle glaucoma patients.

Jpn. J. Ophthalmol. 56(5) , 458-63, (2012)

Our aim was to evaluate the effects of topical carteolol on retinal arterial blood flow (RBF) in patients with primary open-angle glaucoma.Sixteen patients received carteolol topically for 90 days. Changes in RBF in the major retinal artery were evaluated usi...

Cellular cytotoxicity of antiglaucoma drugs in cultured corneal endothelial cells.

Kaohsiung J. Med. Sci. 23(3) , 105-11, (2007)

In this study, the various antiglaucoma drugs including betaxolol, timolol, levobunolol, carteolol, brimonidine, dipivefrin, dorzolamide, brinzolamide, latanoprost, unoprostone, and pilocarpine were used to investigate the effects of cellular cytotoxicity in ...

Effect of carteolol hydrochloride on 24-hour variation of intraocular pressure in normal-tension glaucoma.

Jpn. J. Ophthalmol. 54(2) , 140-3, (2010)

To evaluate the effects of carteolol hydrochloride (carteolol) on 24-h variations in intraocular pressure (IOP) in patients with normal-tension glaucoma (NTG).Twelve patients with NTG were treated with carteolol 2% solution for >or=8 weeks; their pretreatment...

Effects of switching from topical beta-blockers to latanoprost on intraocular pressure in patients with normal-tension glaucoma.

J. Ocul. Pharmacol. Ther. 24(2) , 230-4, (2008)

The effects of switching from topical beta-blockers (beta) to latanoprost (LA) on intraocular pressure (IOP) and IOP-reduction rate (IOP-RR) in patients with normal-tension glaucoma (NTG) were investigated.Sixty (60) NTG patients (60 eyes) were divided into t...

Improvement of the ocular bioavailability of carteolol by ion pair.

J. Ocul. Pharmacol. Ther. 22(5) , 333-9, (2006)

Ocular bioavailability after instillation of carteolol was investigated by ion pair formation, taking into consideration a balance between lipophilicity and water solubility. The octanol/ water partition coefficient (PC(O/W)) and the aqueous humor concentrati...

Effects of a long-acting ophthalmic formulation of carteolol containing alginic acid on the corneal epithelial barrier function and water retentive effect.

J. Ocul. Pharmacol. Ther. 28(2) , 123-8, (2012)

Effects of a long-acting ophthalmic formulation of carteolol containing alginic acid on the corneal epithelial barrier function and its water retentive effect were investigated.Using 10 healthy adult subjects, 2% Mikelan Ophthalmic Solution(®) (MK) was instil...

The possible treatment of migraine with carteolol hydrochloride.

Headache 39(2) , 138-9, (1999)