PF-573228

PF-573228 Structure
PF-573228 structure
Common Name PF-573228
CAS Number 869288-64-2 Molecular Weight 491.486
Density 1.5±0.1 g/cm3 Boiling Point N/A
Molecular Formula C22H20F3N5O3S Melting Point N/A
MSDS Chinese USA Flash Point N/A
Symbol GHS06
GHS06
Signal Word Danger

Integrin-specific control of focal adhesion kinase and RhoA regulates membrane protrusion and invasion.

PLoS ONE 8 , e74659, (2013)

Cell invasion through extracellular matrix (ECM) is a hallmark of the metastatic cascade. Cancer cells require adhesion to surrounding tissues for efficient migration to occur, which is mediated through the integrin family of receptors. Alterations in express...