N-Arachidonyl maleimide

N-Arachidonyl maleimide Structure
N-Arachidonyl maleimide structure
Common Name N-Arachidonyl maleimide
CAS Number 876305-42-9 Molecular Weight 369.540
Density 1.0±0.1 g/cm3 Boiling Point 492.9±34.0 °C at 760 mmHg
Molecular Formula C24H35NO2 Melting Point N/A
MSDS Chinese USA Flash Point 185.2±18.0 °C
Symbol GHS07
GHS07
Signal Word Warning

Crystal structure of the human monoacylglycerol lipase, a key actor in endocannabinoid signaling.

ChemBioChem. 11 , 218-27, (2010)

2-Arachidonoylglycerol plays a major role in endocannabinoid signaling, and is tightly regulated by the monoacylglycerol lipase (MAGL). Here we report the crystal structure of human MAGL. The protein crystallizes as a dimer, and despite structural homologies ...

Characterization of the sulfhydryl-sensitive site in the enzyme responsible for hydrolysis of 2-arachidonoyl-glycerol in rat cerebellar membranes.

Chem. Biol. 12 , 649-56, (2005)

We have previously reported that the endocannabinoid, 2-arachidonoyl-glycerol (2-AG), is hydrolyzed in rat cerebellar membranes by monoglyceride lipase (MGL)-like enzymatic activity. The present study shows that, like MGL, 2-AG-degrading enzymatic activity is...