3-(Trimethylsilyl)propynoic acid

3-(Trimethylsilyl)propynoic acid Structure
3-(Trimethylsilyl)propynoic acid structure
Common Name 3-(Trimethylsilyl)propynoic acid
CAS Number 5683-31-8 Molecular Weight 142.228
Density 1.0±0.1 g/cm3 Boiling Point 219.1±9.0 °C at 760 mmHg
Molecular Formula C6H10O2Si Melting Point 47-49 °C(lit.)
MSDS Chinese USA Flash Point 86.3±18.7 °C
Symbol GHS07
GHS07
Signal Word Warning

Trimethylsilyl-directed 1,3-dipolar cycloaddition reactions in the solid-phase synthesis of 1,2,3-triazoles.

Org. Lett. 7(8) , 1469-72, (2005)

[reaction: see text] A regioselective method for the preparation of 1,5-trisubstituted 1H-1,2,3-triazoles via a 1,3-dipolar cycloaddition of 1-trimethylsilylacetylenes with organoazides is described. Immobilization of the azide on REM resin and subsequent cyc...

One-Pot Synthesis of 3-(Trimethylsilyl) propynamides. Medvedeva AS, et al.

Russ. J. Org. Chem. 46(10) , 1466-1470, (2010)