4-hydroxymethyl imidazole HCL

4-hydroxymethyl imidazole HCL Structure
4-hydroxymethyl imidazole HCL structure
Common Name 4-hydroxymethyl imidazole HCL
CAS Number 32673-41-9 Molecular Weight 134.564
Density 1.311g/cm3 Boiling Point 393.7ºC at 760mmHg
Molecular Formula C4H7ClN2O Melting Point 110 °C
MSDS Chinese USA Flash Point 191.9ºC
Symbol GHS07
GHS07
Signal Word Warning

Structure-based design of imidazole-containing peptidomimetic inhibitors of protein farnesyltransferase.

Org. Biomol. Chem. 4 , 482, (2006)

A series of imidazole-containing peptidomimetic PFTase inhibitors and their co-crystal structures bound to PFTase and FPP are reported. The structures reveal that the peptidomimetics adopt a similar conformation to that of the extended CVIM tetrapeptide, with...