Sodium gentisate
Sodium gentisate structure
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Common Name | Sodium gentisate | ||
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| CAS Number | 4955-90-2 | Molecular Weight | 176.102 | |
| Density | N/A | Boiling Point | 406.9ºC at 760 mmHg | |
| Molecular Formula | C7H5NaO4 | Melting Point | >220ºC (dec) | |
| MSDS | USA | Flash Point | 214ºC | |
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5-Amino-1-naphthol, a novel 1,5-naphthalene derivative matrix suitable for matrix-assisted laser desorption/ionization in-source decay of phosphorylated peptides.
Rapid Commun. Mass Spectrom. 27(1) , 103-8, (2013) Although matrix-assisted laser desorption/ionization in-source decay (MALDI-ISD) is an important method for post-translational modification (PTM) analysis, the conventional matrices, 2,5-dihydroxybenzoic acid (2,5-DHB) and 1,5-diaminonaphthalene (1,5-DAN), ar... |
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Quantitative imaging of a therapeutic peptide in biological tissue sections by MALDI MS.
Bioanalysis 5(5) , 603-12, (2013) Therapeutic peptides and proteins are being increasingly explored as potential therapeutic agents for molecular-targeted therapy, and the requirement for quantitative bioanalytical tools for such molecules has been discussed.The distribution of octreotide, a ... |
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Siderocalin/Lcn2/NGAL/24p3 does not drive apoptosis through gentisic acid mediated iron withdrawal in hematopoietic cell lines.
PLoS ONE 7(8) , e43696, (2012) Siderocalin (also lipocalin 2, NGAL or 24p3) binds iron as complexes with specific siderophores, which are low molecular weight, ferric ion-specific chelators. In innate immunity, siderocalin slows the growth of infecting bacteria by sequestering bacterial fe... |
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Enhancing the identification of phosphopeptides from putative basophilic kinase substrates using Ti (IV) based IMAC enrichment.
Mol. Cell. Proteomics 10(10) , M110.006452, (2011) Metal and metal oxide chelating-based phosphopeptide enrichment technologies provide powerful tools for the in-depth profiling of phosphoproteomes. One weakness inherent to current enrichment strategies is poor binding of phosphopeptides containing multiple b... |
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Crystal structure of 3-hydroxybenzoate 6-hydroxylase uncovers lipid-assisted flavoprotein strategy for regioselective aromatic hydroxylation.
J. Biol. Chem. 288(36) , 26235-45, (2013) 3-Hydroxybenzoate 6-hydroxylase (3HB6H) from Rhodococcus jostii RHA1 is a dimeric flavoprotein that catalyzes the NADH- and oxygen-dependent para-hydroxylation of 3-hydroxybenzoate to 2,5-dihydroxybenzoate. In this study, we report the crystal structure of 3H... |
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[3-hydroxybenzoate and 2,5-dihydroxybenzoate metabolism in Rhodococcus opacus 1CP strain].
Mikrobiologiia 81(3) , 325-31, (2012)
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Discrimination of isobaric Leu/Ile residues by MALDI in-source decay mass spectrometry.
J. Am. Soc. Mass Spectrom. 24(2) , 297-300, (2013) MALDI in-source decay (ISD) has been used for top-down sequencing of proteins. The use of the matrix 1,5-diaminonapthalene (1,5-DAN) gave abundant w ions, which are formed from the unimolecular dissociation of z• radical fragments via α cleavage reaction and ... |
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Salicylic acid 3-hydroxylase regulates Arabidopsis leaf longevity by mediating salicylic acid catabolism.
Proc. Natl. Acad. Sci. U. S. A. 110(36) , 14807-12, (2013) The plant hormone salicylic acid (SA) plays critical roles in plant defense, stress responses, and senescence. Although SA biosynthesis is well understood, the pathways by which SA is catabolized remain elusive. Here we report the identification and character... |
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N-(1-naphthyl) ethylenediamine dinitrate: a new matrix for negative ion MALDI-TOF MS analysis of small molecules.
J. Am. Soc. Mass Spectrom. 23(9) , 1454-60, (2012) An organic salt, N-(1-naphthyl) ethylenediamine dinitrate (NEDN), with rationally designed properties of a strong UV absorbing chromophore, hydrogen binding and nitrate anion donors, has been employed as a matrix to analyze small molecules (m/z < 1000) such a... |
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Quantitative reproducibility of mass spectra in matrix-assisted laser desorption ionization and unraveling of the mechanism for gas-phase peptide ion formation.
J. Mass Spectrom. 48(3) , 299-305, (2013) In a previous study on matrix-assisted laser desorption ionization (MALDI) of peptides using α-cyano-4-hydroxycinnamic acid (CHCA) as a matrix, we found that the patterns of single-shot spectra obtained under different experimental conditions became similar u... |