4-Chloro-1,3-benzenediamine
4-Chloro-1,3-benzenediamine structure
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Common Name | 4-Chloro-1,3-benzenediamine | ||
|---|---|---|---|---|
| CAS Number | 5131-60-2 | Molecular Weight | 142.58600 | |
| Density | 1.345 g/cm3 | Boiling Point | 298.6ºC at 760 mmHg | |
| Molecular Formula | C6H7ClN2 | Melting Point | 87-90 °C(lit.) | |
| MSDS | USA | Flash Point | 134.4ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Phototoxicity of phenylenediamine hair dye chemicals in Salmonella typhimurium TA102 and human skin keratinocytes.
Food Chem. Toxicol. 46(12) , 3780-4, (2008) Phenylenediamines (PD) are dye precursors used to manufacture hair dyes. The three PDs, 1,2-,1,3-, and 1,4-PD and three chlorinated PDs, 4-chloro-1,2-PD, 4-chloro-1,3-PD, and 4,5-dichloro-1,2-PD were studied for their mutagenic effect in Salmonella typhimuriu... |
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4-Chloro-ortho-phenylenediamine and 4-chloro-meta-phenylenediamine.
IARC Monogr. Eval. Carcinog. Risk Chem. Hum. 27 , 81-9, (1982)
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Carcinogenicity of 4-chloro-o-phenylenediamine, 4-chloro-m-phenylenediamine, and 2-chloro-p-phenylenediamine in Fischer 344 rats and B6C3F1 mice.
Carcinogenesis 1(6) , 495-9, (1980) In both male and female Fischer rats, feeding 4-chloro-o-phenylenediamine at 0.5 or 1% in the diet led to a significant increase in hyperplasia, papilloma and carcinoma of the urinary bladder. Neoplastic nodules of the liver and squamous cell papillomas of th... |