4-Chloro-7-nitrobenzofurazan
4-Chloro-7-nitrobenzofurazan structure
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Common Name | 4-Chloro-7-nitrobenzofurazan | ||
|---|---|---|---|---|
| CAS Number | 10199-89-0 | Molecular Weight | 199.551 | |
| Density | 1.7±0.1 g/cm3 | Boiling Point | 333.1±45.0 °C at 760 mmHg | |
| Molecular Formula | C6H2ClN3O3 | Melting Point | 97-99 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 155.3±28.7 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Cytotoxic bile acids, but not cytoprotective species, inhibit the ordering effect of cholesterol in model membranes at physiologically active concentrations.
Biochim. Biophys. Acta 1828(9) , 2152-63, (2013) Submillimolar concentrations of cytotoxic bile acids (BAs) induce cell death via apoptosis. On the other hand, several cytoprotective BAs were shown to prevent apoptosis in the same concentration range. Still, the mechanisms by which BAs trigger these opposit... |
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Evaluation of a microchip electrophoresis-mass spectrometry platform deploying a pressure-driven make-up flow.
J. Chromatogr. A. 1285 , 159-64, (2013) Integration of a pressure-driven make-up flow (MUF) into a microchip electrophoresis (MCE) platform in order to facilitate its coupling with electrospray ionization-mass spectrometric detection (ESI-MS) is described. In the glass/PDMS hybrid microchip, a MUF ... |
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Determination of hinokitiol in skin lotion by high-performance liquid chromatography-ultraviolet detection after precolumn derivatization with 4-fluoro-7-nitro-2,1,3-benzoxadiazole.
J. Cosmet. Sci. 64(5) , 381-9, (2013) Hinokitiol, a potent, broad-spectrum antibacterial agent, is a component of various personal care products. In this study, the concentration of hinokitiol in skin lotion was analyzed by means of high-performance liquid chromatography-ultraviolet detection (38... |
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Determination of kojic acid in a skin-whitening cosmetic by high-performance liquid chromatography coupled with ultraviolet detection after pre-column derivatization with 4-fluoro-7-nitro-2,1,3-benzoxadiazole.
J. Cosmet. Sci. 63(3) , 205-12, (2012) Various methods for the determination of kojic acid (KA), a skin-whitening agent, have been reported by high-performance liquid chromatography (HPLC). In this study, the concentration of KA in a skin-whitening cosmetic was analyzed by HPLC with ultraviolet de... |
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Simple and sensitive high performance liquid chromatography method with fluorescence detection for therapeutic drug monitoring of topiramate.
Acta Chim. Slov. 62 , 411-9, (2015) A simple, sensitive, accurate, precise and inexpensive HPLC method with fluorescence detection, suitable for routine therapeutic drug monitoring (TDM) of an antiepileptic drug topiramate, was developed and validated. The determination of plasma topiramate con... |
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Central alarin ameliorated insulin resistance of adipocytes in type 2 diabetic rats.
J. Endocrinol. 223(3) , 217-25, (2014) Alarin, a regulatory peptide, belongs to the galanin family and plays the same regulatory roles as galanin in orexigenic activity and energy metabolism. Our previous studies had found that galanin might facilitate insulin sensitivity via activation of its cen... |
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pH-dependent promotion of phospholipid flip-flop by the KcsA potassium channel.
Biochim. Biophys. Acta 1848(1 Pt A) , 145-50, (2015) KcsA is a pH-dependent potassium channel that is activated at acidic pH. The channel undergoes global conformational changes upon activation. We hypothesized that the open-close conformational changes of the transmem brane region could promote the flip-flop o... |
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Temperature- and pH-Dependent Shattering: Insoluble Fatty Ammonium Phosphate Films at Water-Oil Interfaces.
Langmuir 31 , 9312-24, (2015) We study the films formed by tetradecylamine (TDA) at the water-dodecane interface in the presence of hydrogen phosphate ions. Using Fourier transform infrared spectroscopy (FTIR), interfacial shear rheology, confocal fluorescence microscopy, cryo-scanning el... |
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Isoorientin reverts TNF-α-induced insulin resistance in adipocytes activating the insulin signaling pathway.
Endocrinology 153(11) , 5222-30, (2012) Isoorientin (ISO) is a plant C-glycosylflavonoid with purported antidiabetic effects but unexplored mechanisms of action. To gain insight into its antidiabetic mechanisms, we assayed nontoxic ISO concentrations on the 2-(N-(7-nitrobenz-2-oxa-1, 3-diazol-4-yl)... |
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Evaluation of the fluorescent probes Nile Red and 25-NBD-cholesterol as substrates for steroid-converting oxidoreductases using pure enzymes and microorganisms.
FEBS J. 280(13) , 3109-19, (2013) The fluorescent probes Nile Red (nonsteroidal dye) and 25-{N-[(7-nitrobenz-2-oxa-1,3-diazol-4-yl)-methyl]amino}-27-norcholesterol (25-NBD-cholesterol) (a cholesterol analog) were evaluated as novel substrates for steroid-converting oxidoreductases. Docking si... |