2-Aminobenzophenone

2-Aminobenzophenone Structure
2-Aminobenzophenone structure
Common Name 2-Aminobenzophenone
CAS Number 2835-77-0 Molecular Weight 197.24
Density 1.2±0.1 g/cm3 Boiling Point 383.7±25.0 °C at 760 mmHg
Molecular Formula C13H11NO Melting Point 103-107 °C(lit.)
MSDS Chinese USA Flash Point 185.9±23.2 °C
Symbol GHS07
GHS07
Signal Word Warning

B-ring-aryl substituted luotonin A analogues with a new binding mode to the topoisomerase 1-DNA complex show enhanced cytotoxic activity.

PLoS ONE 9(5) , e95998, (2014)

Topoisomerase 1 inhibition is an important strategy in targeted cancer chemotherapy. The drugs currently in use acting on this enzyme belong to the family of the camptothecins, and suffer severe limitations because of their low stability, which is associated ...

Effects of conformational restriction of 2-amino-3-benzoylthiophenes on A(1) adenosine receptor modulation.

J. Med. Chem. 53 , 6550-9, (2010)

2-Amino-3-benzoylthiophenes (2A3BTs) have been widely reported to act as allosteric enhancers (AEs) at the A(1) adenosine receptor (A(1)AR). Herein we describe the synthesis of a series of 1-aminoindeno[1,2-c]thiophen-8-ones and a series of (2-aminoindeno[2,1...