D-Glucose 6-Phosphate

D-Glucose 6-Phosphate Structure
D-Glucose 6-Phosphate structure
Common Name D-Glucose 6-Phosphate
CAS Number 56-73-5 Molecular Weight 260.13600
Density 1.97g/cm3 Boiling Point 564.1ºC at 760 mmHg
Molecular Formula C6H13O9P Melting Point N/A
MSDS Chinese USA Flash Point 295ºC
Symbol GHS05
GHS05
Signal Word Danger

Probing myo-inositol 1-phosphate synthase with multisubstrate adducts.

Org. Biomol. Chem. 10(48) , 9601-19, (2012)

The synthesis of a series of carbohydrate-nucleotide hybrids, designed to be multisubstrate adducts mimicking myo-inositol 1-phosphate synthase first oxidative transition state, is reported. Their ability to inhibit the synthase has been assessed and results ...

Reduced cellular Mg__ content enhances hexose 6-phosphate dehydrogenase activity and expression in HepG2 and HL-60 cells.

Arch. Biochem. Biophys. 548 , 11-9, (2014)

We have reported that Mg(2+) dynamically regulates glucose 6-phosphate entry into the endoplasmic reticulum and its hydrolysis by the glucose 6-phosphatase in liver cells. In the present study, we report that by modulating glucose 6-phosphate entry into the e...

Teaching NeuroImages: diagnostic utility of FDG-PET in neurolymphomatosis.

Neurology 81(1) , e3, (2013)

Allosteric regulation of the partitioning of glucose-1-phosphate between glycogen and trehalose biosynthesis in Mycobacterium tuberculosis.

Biochim. Biophys. Acta 1850(1) , 13-21, (2015)

Mycobacterium tuberculosis is a pathogenic prokaryote adapted to survive in hostile environments. In this organism and other Gram-positive actinobacteria, the metabolic pathways of glycogen and trehalose are interconnected.In this work we show the production,...

Transcriptome analysis suggests that starch synthesis may proceed via multiple metabolic routes in high yielding potato cultivars.

PLoS ONE 7(12) , e51248, (2012)

Glucose-6-phosphate is imported into the amyloplast of potato tubers and thought to constitute the precursor for starch synthesis in potato tubers. However, recently it was shown that glucose-1-phosphate can also be imported into the amyloplast and incorporat...

Post-slaughter changes in ATP metabolites, reducing and phosphorylated sugars in chicken meat.

Meat Science 94(1) , 55-62, (2013)

The formation of ATP breakdown products in chicken M. pectoralis major post-slaughter is reported. The concentrations of metabolites were followed in chicken breast throughout the carcass processing post-slaughter and during chilled storage. The concentration...

Biocatalytic production of alpha-hydroxy ketones and vicinal diols by yeast and human aldo-keto reductases.

Chem. Biol. Interact. 202(1-3) , 195-203, (2013)

The α-hydroxy ketones are used as building blocks for compounds of pharmaceutical interest (such as antidepressants, HIV-protease inhibitors and antitumorals). They can be obtained by the action of enzymes or whole cells on selected substrates, such as diketo...

Evidence that adrenal hexose-6-phosphate dehydrogenase can effect microsomal P450 cytochrome steroidogenic enzymes.

Biochim. Biophys. Acta 1833(9) , 2039-44, (2013)

The role of adrenal hexose-6-phosphate dehydrogenase in providing reducing equivalents to P450 cytochrome steroidogenic enzymes in the endoplasmic reticulum is uncertain. Hexose-6-phosphate dehydrogenase resides in the endoplasmic reticulum lumen and co-local...

The ancestral activation promiscuity of ADP-glucose pyrophosphorylases from oxygenic photosynthetic organisms.

BMC Evol. Biol. 13 , 51, (2013)

ADP-glucose pyrophosphorylase (ADP-Glc PPase) catalyzes the first committed step in the synthesis of glycogen in bacteria and starch in algae and plants. In oxygenic photosynthetic organisms, ADP-Glc PPase is mainly activated by 3-phosphoglycerate (3-PGA) and...

In Saccharomyces cerevisiae fructose-1,6-bisphosphate contributes to the Crabtree effect through closure of the mitochondrial unspecific channel.

Arch. Biochem. Biophys. 555-556 , 66-70, (2014)

In Saccharomyces cerevisiae addition of glucose inhibits oxygen consumption, i.e. S. cerevisiae is Crabtree-positive. During active glycolysis hexoses-phosphate accumulate, and probably interact with mitochondria. In an effort to understand the mechanism unde...