![]() 1,2-Benzenediamine,hydrochloride (1:2) structure
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Common Name | 1,2-Benzenediamine,hydrochloride (1:2) | ||
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CAS Number | 615-28-1 | Molecular Weight | 181.06300 | |
Density | N/A | Boiling Point | 257ºC at 760 mmHg | |
Molecular Formula | C6H10Cl2N2 | Melting Point | 258ºC (dec.)(lit.) | |
MSDS | Chinese USA | Flash Point | 124.9ºC | |
Symbol |
![]() ![]() ![]() GHS07, GHS08, GHS09 |
Signal Word | Warning |
Enhancing the anti-inflammatory activity of chalcones by tuning the Michael acceptor site.
Org. Biomol. Chem. 13(10) , 3040-7, (2015) Inflammatory signaling pathways orchestrate the cellular response to infection and injury. These pathways are known to be modulated by compounds that alkylate cysteinyl thiols. One class of phytochemicals with strong thiol alkylating activity is the chalcones... |
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The combined role of galactose-deficient IgA1 and streptococcal IgA-binding M Protein in inducing IL-6 and C3 secretion from human mesangial cells: implications for IgA nephropathy.
J. Immunol. 193(1) , 317-26, (2014) IgA nephropathy (IgAN) is characterized by mesangial cell proliferation and extracellular matrix expansion associated with immune deposits consisting of galactose-deficient polymeric IgA1 and C3. We have previously shown that IgA-binding regions of streptococ... |
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Serodiagnosis of Toxoplasma gondii infection in farm animals (horses, swine, and sheep) by enzyme-linked immunosorbent assay using chimeric antigens.
Parasitol. Int. 64 , 288-94, (2015) Toxoplasma gondii infects all warm-blooded animals including humans, causing serious public health problems and great economic loss in the animal husbandry. Commonly used serological tests for diagnosis of toxoplasmosis involve preparation of whole Toxoplasma... |
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Production and preclinical evaluation of Plasmodium falciparum MSP-119 and MSP-311 chimeric protein, PfMSP-Fu24.
Clin. Vaccine Immunol. 21(6) , 886-97, (2014) A Plasmodium falciparum chimeric protein, PfMSP-Fu24, was constructed by genetically coupling immunodominant, conserved regions of two merozoite surface proteins, the 19-kDa region C-terminal region of merozoite surface protein 1 (PfMSP-119) and an 11-kDa con... |
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Pathogenicity and transmissibility of novel reassortant H3N2 influenza viruses with 2009 pandemic H1N1 genes in pigs.
J. Virol. 89(5) , 2831-41, (2015) At least 10 different genotypes of novel reassortant H3N2 influenza viruses with 2009 pandemic H1N1 [A(H1N1)pdm09] gene(s) have been identified in U.S. pigs, including the H3N2 variant with a single A(H1N1)pdm09 M gene, which has infected more than 300 people... |
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Limited effect of recombinant human mannose-binding lectin on the infection of novel influenza A (H7N9) virus in vitro.
Biochem. Biophys. Res. Commun. 458(1) , 77-81, (2015) Mannose-binding lectin (MBL), a pattern-recognition molecule in serum, recognizes specific hexose sugars rich in mannose and N-acetylglucosamine on bacterium, yeasts, viruses as well as apoptotic cells. It has been well-identified that MBL has antiviral effec... |
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Generation of an anti-EpCAM antibody and epigenetic regulation of EpCAM in colorectal cancer.
Int. J. Oncol. 46(4) , 1788-800, (2015) We have generated a novel monoclonal antibody (mAb), OCAb9-1, which specifically binds to various types of cancer cell lines, but not to normal cells. According to the results of immunoaffinity chromatography, LC-MS/MS analysis, co-immunoprecipitation, and RN... |
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Zingiber mioga (Thunb.) Roscoe attenuates allergic asthma induced by ovalbumin challenge.
Mol. Med. Report. 12 , 4538-45, (2015) Zingiber mioga (Thunb.) Roscoe (ZM) is a traditional medicine, used to treat inflammatory diseases. The present study aimed to evaluate the inhibitory effects of ZM on the inflammatory response in lipopolysaccharide (LPS)‑stimulated RAW264.7 murine macrophage... |
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Structural characterization of a protective epitope spanning A(H1N1)pdm09 influenza virus neuraminidase monomers.
Nat. Commun. 6 , 6114, (2015) A(H1N1)pdm09 influenza A viruses predominated in the 2013-2014 USA influenza season, and although most of these viruses remain sensitive to Food and Drug Administration-approved neuraminidase (NA) inhibitors, alternative therapies are needed. Here we show tha... |
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A novel plant-produced Pfs25 fusion subunit vaccine induces long-lasting transmission blocking antibody responses.
Hum. Vaccin. Immunother. 11(1) , 124-32, (2015) Malaria transmission blocking vaccines (TBV) directed against proteins expressed on sexual stages of Plasmodium falciparum in the mosquito midgut are considered an effective means to reduce malaria transmission. Antibodies induced by TBV block sporogonic deve... |