3-aminopropionitrile fumarate
3-aminopropionitrile fumarate structure
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Common Name | 3-aminopropionitrile fumarate | ||
|---|---|---|---|---|
| CAS Number | 2079-89-2 | Molecular Weight | 186.165 | |
| Density | N/A | Boiling Point | 355.5ºC at 760 mmHg | |
| Molecular Formula | C7H10N2O4 | Melting Point | 177 °C (dec.)(lit.) | |
| MSDS | Chinese USA | Flash Point | 183ºC | |
| Symbol |
GHS08 |
Signal Word | Danger | |
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The Nox1/4 Dual Inhibitor GKT137831 or Nox4 Knockdown Inhibits Angiotensin-II-Induced Adult Mouse Cardiac Fibroblast Proliferation and Migration. AT1 Physically Associates With Nox4.
J. Cell Physiol. 231 , 1130-41, (2016) Both oxidative stress and inflammation contribute to chronic hypertension-induced myocardial fibrosis and adverse cardiac remodeling. Here we investigated whether angiotensin (Ang)-II-induced fibroblast proliferation and migration are NADPH oxidase (Nox) 4/RO... |
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Inhibitory effects of prostaglandin E2 on collagen synthesis and cell proliferation in human stellate cells from pancreatic head adenocarcinoma.
BMC Cancer 14 , 413, (2014) Several studies have described an increased cyclooxygenase-2 (COX-2) expression in pancreatic cancer, but the role of COX-2 in tumour development and progression is not clear. The aim of the present study was to examine expression of COX-2 in cancer cells and... |
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Structural and functional changes in lung tissue of mice fed with beta-aminopropionitrile fumarate, L-3-cis-hydroxyproline, and L-4-cis-hydroxyproline.
Respiration 54(2) , 132-8, (1988) Structural and functional changes in lung tissue of mice fed with beta-aminopropionitrile fumarate, L-3-cis-hydroxyproline, and L-4-cis-hydroxyproline. We fed 0.1% solutions of 3-cis-hydroxyproline (3cisHP), 4-cis-hydroxyproline (4cisHP) or beta-aminopropioni... |
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Possibilities for the therapeutic control of fibrosis.
Br. J. Dermatol. 112(3) , 363-71, (1985)
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Effect of topical beta APN application on evoked potential conduction in rat sciatic nerve and spinal cord.
Surg. Neurol. 28(3) , 201-7, (1987) The purpose of this study is to evaluate possible toxic effects of beta-aminopropionitrile fumarate (beta APN), a lathyrogenic agent that inhibits fibrosis. This drug has been considered for use as an adjunct to surgical repair after topical application upon ... |
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The effect of beta-aminoproprionitrile on the lingual artery and aorta of the rat: a light microscopic study.
J. Biol. Buccale 10(3) , 227-35, (1982) The effects of chronic toxicity of beta-aminoproprionitrile (BAPN) on the lingual artery and aorta of the rat were compared. Thirty-two three week old weanling male white Wistar rats were given 1 g/kg/day (for five days weekly) of a 40% saturated solution of ... |
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Healing of skin incision wounds treated with topically applied BAPN free base in the rat.
Exp. Mol. Pathol. 39(2) , 154-62, (1983) beta-Aminopropionitrile as free base (BAPN) was applied onto the incised or intact skin of rats at the dose of 5, 20, 100, and 200 microliters for 9 days, twice daily. Breaking strength of the skin wound or intact skin was significantly reduced at doses of 20... |
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Effect of parathyroid extract and of glutaurine (gamma-L-glutamyl-taurine) on the manifestations of osteolathyrism.
Endokrinologie 75(3) , 350-6, (1980) BAPN-induced osteolathyrism in young and older male rats was examined for its responses to parathormone-free, gel-filtered bovine parathyroid extract (extract P) and to glutaurine (gamma-L-glutamyl-taurine), the latter being a hitherto unknown putative hormon... |
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On the mechanisms of beta-aminopropionitrile toxicity.
J. Surg. Res. 31(2) , 151-5, (1981)
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Topical application of B-aminopropionitrile.
Life Sci. 29(24) , 2553-60, (1981)
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