Methyl phosphorodichloridate

Methyl phosphorodichloridate Structure
Methyl phosphorodichloridate structure
Common Name Methyl phosphorodichloridate
CAS Number 677-24-7 Molecular Weight 148.913
Density 1.5±0.1 g/cm3 Boiling Point 167.8±9.0 °C at 760 mmHg
Molecular Formula CH3Cl2O2P Melting Point N/A
MSDS USA Flash Point 3.0±26.4 °C
Symbol GHS05
GHS05
Signal Word Danger

Enzymatic release of antitumor ether lipids by specific phospholipase A2 activation of liposome-forming prodrugs.

J. Med. Chem. 47(7) , 1694-703, (2004)

An enzymatically activated liposome-based drug-delivery concept involving masked antitumor ether lipids (AELs) has been investigated. This concept takes advantage of the cytotoxic properties of AEL drugs as well as the membrane permeability enhancing properti...

Synthesis of 8-(2"-hydroxyethoxy)adenosine-5',2"-phosphate derivative.

Nucleic Acids Symp. Ser. (17) , 61-3, (1986)

Reaction of 8-bromo-2',3'-O-isopropylidene-5'-O-(tetrahydropyran-2-yl) adenosine (Ib) with lithium 2-(tetrahydropyran-2-yloxy) ethoxide, followed by removal of the tetrahydropyran-2-yl groups, afforded 8-(2''-hydroxyethoxy)-2',3'-O-isopropylideneadenosine (II...

Synthesis of oligosaccharides corresponding to Vibrio cholerae O139 polysaccharide structures containing dideoxy sugars and a cyclic phosphate.

Org. Biomol. Chem. 4(7) , 1236-41, (2006)

A spacer-equipped tetrasaccharide, p-aminocyclohexylethyl alpha-l-Colp-(1-->2)-beta-d-Galp-(1-->3)-[alpha-l-Colp-(1-->4)]-beta-D-GlcpNAc, containing a 4,6-cyclic phosphate in the galactose residue, has been synthesised. The structure corresponds to a part of ...

Syntheses of Ortho-Hydroxymethylpyridinols and Dioxaphosphorino [m, nx] pyridines. Leroy F, et al.

Synth. Commun. 26(12) , 2257-72, (1996)