2-linoleoylglycerol

2-linoleoylglycerol Structure
2-linoleoylglycerol structure
Common Name 2-linoleoylglycerol
CAS Number 3443-82-1 Molecular Weight 354.524
Density 1.0±0.1 g/cm3 Boiling Point 485.0±40.0 °C at 760 mmHg
Molecular Formula C21H38O4 Melting Point 9ºC
MSDS N/A Flash Point 157.0±20.8 °C
Symbol GHS02 GHS07
GHS02, GHS07
Signal Word Danger

TRPV4 inhibition counteracts edema and inflammation and improves pulmonary function and oxygen saturation in chemically induced acute lung injury.

Am. J. Physiol. Lung Cell. Mol. Physiol. 307(2) , L158-72, (2014)

The treatment of acute lung injury caused by exposure to reactive chemicals remains challenging because of the lack of mechanism-based therapeutic approaches. Recent studies have shown that transient receptor potential vanilloid 4 (TRPV4), an ion channel expr...

Targeted lipidomics in Drosophila melanogaster identifies novel 2-monoacylglycerols and N-acyl amides.

PLoS ONE 8 , e67865, (2013)

Lipid metabolism is critical to coordinate organ development and physiology in response to tissue-autonomous signals and environmental cues. Changes to the availability and signaling of lipid mediators can limit competitiveness, adaptation to environmental st...

GPR55, a G-protein coupled receptor for lysophosphatidylinositol, plays a role in motor coordination.

PLoS ONE 8 , e60314, (2013)

The G-protein coupled receptor 55 (GPR55) is activated by lysophosphatidylinositols and some cannabinoids. Recent studies found prominent roles for GPR55 in neuropathic/inflammatory pain, cancer and bone physiology. However, little is known about the role of ...