Sulbactam sodium
Sulbactam sodium structure
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Common Name | Sulbactam sodium | ||
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| CAS Number | 69388-84-7 | Molecular Weight | 255.223 | |
| Density | N/A | Boiling Point | 567.7ºC at 760 mmHg | |
| Molecular Formula | C8H10NNaO5S | Melting Point | 121-123 °C(lit.) | |
| MSDS | N/A | Flash Point | 297.1ºC | |
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Clinical response at Day 3 of therapy and economic outcomes in hospitalized patients with acute bacterial skin and skin structure infection (ABSSSI).
Curr. Med. Res. Opin. 29(7) , 869-77, (2013) The FDA recently issued guidance for the types of infections that should be included in trials to support an indication for antibacterial treatment. The latest FDA guidance recommends assessing response to drug therapy at 48 to 72 hours as the primary endpoin... |
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Antibiotic regimens for management of intra-amniotic infection.
Cochrane Database Syst. Rev. 12 , CD010976, (2014) Chorioamnionitis is a common infection that affects both mother and infant. Infant complications associated with chorioamnionitis include early neonatal sepsis, pneumonia, and meningitis. Chorioamnionitis can also result in maternal morbidity such as pelvic i... |
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Anaerobiospirillum succiniciproducens-induced bacteremia in a healthy man.
Am. J. Emerg. Med. 32(7) , 812.e1-3, (2014) Anaerobiospirillum succiniciproducens is rarely associated with bacteremia but results in significant mortality. Almost all reported bacteremia cases have occurred in immunocompromised hosts, such as those with alcoholic liver disease, atherosclerosis, recent... |
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In vitro pharmacodynamics of human-simulated exposures of ampicillin/sulbactam, doripenem and tigecycline alone and in combination against multidrug-resistant Acinetobacter baumannii.
J. Antimicrob. Chemother. 68(10) , 2296-304, (2013) Multidrug resistance is common among Acinetobacter baumannii, limiting the available options used to treat infections caused by this organism. The objective of this study was to compare monotherapy and combination therapy with ampicillin/sulbactam, doripenem ... |
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Evaluation of cutaneous palpebral anthrax.
Cutan. Ocul. Toxicol. 32(4) , 294-8, (2013) Anthrax is a rare disease caused by Bacillus anthracis. Antrax is zoonotic disease and is often encountered in persons engaged in animal husbandry. Cutaneous anthrax is approximately 95% of anthrax in humans. Palbebral involvement is rare.In this study, we ai... |
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New insights in the production of aerosol antibiotics. Evaluation of the optimal aerosol production system for ampicillin-sulbactam, meropenem, ceftazidime, cefepime and piperacillin-tazobactam.
Int. J. Pharm. 455(1-2) , 182-8, (2013) Several aerosol antibiotics are on the market and several others are currently being evaluated. Aim of the study was to evaluate the aerosol droplet size of five different antibiotics for future evaluation as an aerosol administration.The nebulizers Sunmist(®... |
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Interaction between caspofungin or voriconazole and cefoperazone-sulbactam or piperacillin-tazobactam by in vitro and in vivo methods.
APMIS 122(5) , 412-7, (2014) Immunosuppressive patients are at risk of fungal and bacterial infections. Therefore, these patients receive prophylactic, preemptive, empirical or target antifungal and concomitant antibiotic therapy. To this end, caspofungin (CAS) or voriconazole (VRC) anti... |
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Comparative in-vitro activity of cefoperazone-tazobactam and cefoperazone-sulbactam combinations against ESBL pathogens in respiratory and urinary infections.
J. Assoc. Physicians India 60 , 22-4, (2012) The emergence and subsequent widespread dissemination of bacterial resistance to a variety of beta-lactam antibiotics by the elaboration of ESBL (Extended Spectrum Beta Lactamase) poses a serious threat to the effective use of beta lactam antibiotics and ceph... |
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[Application of gepacef comby for an acute surgical diseases of organs of the hepatopancreatobiliary zone].
Klin. Khir. (1) , 40-3, (2013) The experience of application of the III generation cephalosporine Gepacef comby (cefoperazone/sulbactam, manufactured by Corporation "ARTERIUM", Ukraine) in complex of empirical therapy of an acute surgical diseases of the hepatopancreatobiliary zone organs ... |
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In vitro activity of cefoperazone-sulbactam combination against gram negative bacilli.
Nepal Med. Coll. J. 14(1) , 5-8, (2012) Cefoperazone is a â-lactam antimicrobial and Sulbactam is an irreversible â-lactamase inhibitor. The objective of this study was to know the susceptibility pattern of gram negative bacilli (GNB) towards cefoperazone-sulbactum. All GNB isolated from different ... |