Tiaprofenic Acid

Tiaprofenic Acid Structure
Tiaprofenic Acid structure
Common Name Tiaprofenic Acid
CAS Number 33005-95-7 Molecular Weight 260.30800
Density 1.29 g/cm3 Boiling Point 450.3ºC at 760 mmHg
Molecular Formula C14H12O3S Melting Point 96° (isopropyl ether)
MSDS N/A Flash Point 226.1ºC

The effect of terpenes on percutaneous absorption of tiaprofenic acid gel.

Arch. Pharm. Res. 33(11) , 1781-8, (2010)

Tiaprofenic acid is a potent analgesic and nonsteroidal anti-inflammatory drug (NSAID) and like any other nonsteroidal anti-inflammatory drug, oral administration of the conventional dosage forms of tiaprofenic acid invariably causes gastrointestinal side eff...

Time-resolved spectroscopic study of the photochemistry of tiaprofenic acid in a neutral phosphate buffered aqueous solution from femtoseconds to final products.

J. Phys. Chem. B 117(3) , 811-24, (2013)

The photo-decarboxylation and overall reaction mechanism of tiaprofenic acid (TPA) was investigated by femtosecond transient absorption (fs-TA), nanosecond transient absorption (ns-TA), and nanosecond time-resolved resonance Raman (ns-TR(3)) spectroscopic exp...

[New technologies in laparoscopic surgery].

Chirurg. 72(3) , 252-60, (2001)

The technology associated with endoscopic surgery continues to evolve as a result of industrial R & D and research within academic surgical departments with interest in surgical endoscopic and remote handling technology. Some of the developments in the last t...

Symposium on therapeutic aspects of tiaprofenic acid.

Drugs 35 Suppl 1 , 1-3, (1988)

The effect of flurbiprofen and tiaprofenic acid on serum cytokine levels of patients with osteoarthrosis.

Acta Orthop. Scand. 72(5) , 499-502, (2001)

39 patients with active knee osteoarthrosis, chosen according to ACR criteria, were assigned to receive flurbiprofen (n 12, 2 x 100 mg), tiaprofenic acid (n 14, 2 x 300 mg) and placebo (n 13) in a 3-week, placebo-controlled study. All patients completed the s...

Tiaprofenic acid. A reappraisal of its pharmacological properties and use in the management of rheumatic diseases.

Drugs 50(6) , 1050-75, (1995)

Tiaprofenic acid is a nonsteroidal anti-inflammatory drug (NSAID) used in the treatment of patients with rheumatic diseases and other clinical conditions of pain and inflammation. Like other propionic acid derivatives, tiaprofenic acid is effective and genera...

Single dose oral tiaprofenic acid for acute postoperative pain in adults.

Cochrane Database Syst. Rev. (4) , CD007542, (2009)

Tiaprofenic acid is a a non-steroidal anti-inflammatory drug (NSAID). It is widely available around the world, with indications for osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, periarticular disorders, and strains and sprains. This review sou...

Tiaprofenic acid-photosensitized damage to nucleic acids: a mechanistic study using complementary in vitro approaches.

Photochem. Photobiol. 71(5) , 499-505, (2000)

In order to determine whether or not tiaprofenic acid (TPA) could cause cellular DNA damage, human fibroblasts were irradiated in the presence of the drug and subsequently examined by means of the comet assay. This led to the observation that TPA actually sen...

Involvement of type I and type II mechanisms in the linoleic acid peroxidation photosensitized by tiaprofenic acid.

J. Photochem. Photobiol. B, Biol. 58(1) , 1-5, (2000)

Analysis of the photomixtures resulting from irradiation of aqueous solutions of linoleic acid sensitized by tiaprofenic acid (TPA) or its major photoproduct (DTPA) by HPLC has shown the formation of all the four possible conjugated dienic hydroperoxides. Acc...

Tiaprofenic acid-induced cystitis--three cases and a literature review.

Scand. J. Urol. Nephrol. 33(6) , 408-10, (1999)

Tiaprofenic acid is a non-steroidal anti-inflammatory drug that may cause severe non-bacterial cystitis. Three cases are described and the literature is reviewed.