Cyclocytidine Hydrochloride

Cyclocytidine Hydrochloride Structure
Cyclocytidine Hydrochloride structure
Common Name Cyclocytidine Hydrochloride
CAS Number 10212-25-6 Molecular Weight 261.662
Density 2.01 g/cm3 Boiling Point 442ºC at 760 mmHg
Molecular Formula C9H12ClN3O4 Melting Point 269-270ºC
MSDS Chinese USA Flash Point 221.1ºC

Cytosine-based nucleoside analogs are selectively lethal to DNA mismatch repair-deficient tumour cells by enhancing levels of intracellular oxidative stress.

Br. J. Cancer 108(4) , 983-92, (2013)

DNA mismatch repair deficiency is present in a significant proportion of a number of solid tumours and is associated with distinct clinical behaviour.To identify the therapeutic agents that might show selectivity for mismatch repair-deficient tumour cells, we...

Tyramine-like effect of cyclocytidine (2,2'-anhydro-1-β-arabinofuranosylcytosine hydrochloride), an antineoplastic agent Oguro, K., Hashimoto, K.

J. Exp. Med. 124 , 83-90, (1978)