Serinol
Serinol structure
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Common Name | Serinol | ||
|---|---|---|---|---|
| CAS Number | 534-03-2 | Molecular Weight | 91.109 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 266.7±20.0 °C at 760 mmHg | |
| Molecular Formula | C3H9NO2 | Melting Point | 52-55 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 115.1±21.8 °C | |
| Symbol |
GHS05 |
Signal Word | Danger | |
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Novel Redox-Responsive Amphiphilic Copolymer Micelles for Drug Delivery: Synthesis and Characterization.
AAPS J. 17 , 1357-68, (2015) A novel redox-responsive amphiphilic polymer was synthesized with bioreductive trimethyl-locked quinone propionic acid for a potential triggered drug delivery application. The aim of this study was to synthesize and characterize the redox-responsive amphiphil... |
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Design, synthesis and characterization of novel binary V(V)-Schiff base materials linked with insulin-mimetic vanadium-induced differentiation of 3T3-L1 fibroblasts to adipocytes. Structure-function correlations at the molecular level.
J. Inorg. Biochem. 147 , 99-115, (2015) Among the various roles of vanadium in the regulation of intracellular signaling, energy metabolism and insulin mimesis, its exogenous activity stands as a contemporary challenge currently under investigation and a goal to pursue as a metallodrug against Diab... |
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Phospholipase D-catalyzed synthesis of new phospholipids with polar head groups.
Chem. Phys. Lipids 152(2) , 71-7, (2008) A series of new phospholipids with polar head groups have been synthesized by enzymatic transphosphatidylation of 1,2-dioleoyl-sn-glycerophosphocholine and identified by 1H NMR and MALDI-TOF-MS. The acceptor alcohols were N- or C2-substituted derivatives of e... |
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Reactions of serine palmitoyltransferase with serine and molecular mechanisms of the actions of serine derivatives as inhibitors.
Biochemistry 43(4) , 1082-92, (2004) Serine palmitoyltransferase (SPT) is a key enzyme in sphingolipid biosynthesis and catalyzes the decarboxylative condensation of L-serine and palmitoyl coenzyme A to 3-ketodihydrosphingosine. We have succeeded in the overproduction of a water-soluble homodime... |
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Structures of a unique O-polysaccharide of Edwardsiella tarda PCM 1153 containing an amide of galacturonic acid with 2-aminopropane-1,3-diol and an abequose-containing O-polysaccharide shared by E. tarda PCM 1145, PCM 1151 and PCM 1158.
Carbohydr. Res. 355 , 56-62, (2012) Lipopolysaccharides of four strains of Edwardsiella tarda were degraded by mild acid hydrolysis, and the released O-polysaccharides were isolated by GPC and studied by sugar and methylation analyses along with (1)H and (13)C NMR spectroscopy, including 2D (1)... |
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Effects of the serine analogues isoserine and serinol on interleukin-2 synthesis and phospholipid metabolism in a human T cell line Jurkat.
J. Lipid Mediat. 3(1) , 79-89, (1991) Phosphatidylserine has been implicated both in the regulation of protein kinase C activity and in the regulation of T lymphocyte activation. Taking into account the fact that some serine analogues modify the activity of the base exchange enzyme system respons... |
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Efficient, stereoselective synthesis of oxazolo[3,2-a]pyrazin-5-ones: novel bicyclic lactam scaffolds from the bicyclocondensation of 3-aza-1,5-ketoacids and amino alcohols.
Org. Lett. 5(15) , 2727-30, (2003) [reaction: see text] The bicyclocondensation of 3-aza-1,5-ketoacids and amino alcohols furnished novel oxazolo[3,2-a]pyrazin-5-one scaffolds possessing angular, ring junction substituents in high yield with excellent levels of substrate-based diastereocontrol... |
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Weak affinity ligands selection using quartz crystal microbalance biosensor: multi-hydroxyl amine ligands for protein separation.
Anal. Chim. Acta 703(2) , 250-6, (2011) Multi-hydroxyl amines including tris(hydroxymethyl)aminomethane (Tris), serinol and ethanolamine were selected as weak affinity ligands using a rapid screening by quartz crystal microbalance (QCM) biosensor. Based on the specific recognition between the ligan... |
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Biotechnological conversion of glycerol to 2-amino-1,3-propanediol (serinol) in recombinant Escherichia coli.
Appl. Microbiol. Biotechnol. 93(1) , 357-65, (2012) Microbial conversion is an important technology for the refinement of renewable resources. Here, we describe the biotechnological conversion of glycerol to 2-amino-1,3-propanediol (serinol), a relevant intermediate in several chemical syntheses processes. Eit... |
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Synthesis and evaluation of RNA transesterification efficiency using stereospecific serinol-terpyridine conjugates.
Nucleosides Nucleotides Nucleic Acids 24(9) , 1309-23, (2005) Six novel artificial ribonucleases were synthesized employing a stereochemically pure abasic serinol backbone residue for attachment of the RNA transesterification agent copper(II) terpyridine. These stereochemically pure abasic residues were synthesized as p... |