2(3H)-Furanone,3-aminodihydro-(8CI,9CI)
2(3H)-Furanone,3-aminodihydro-(8CI,9CI) structure
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Common Name | 2(3H)-Furanone,3-aminodihydro-(8CI,9CI) | ||
|---|---|---|---|---|
| CAS Number | 1192-20-7 | Molecular Weight | 337.49700 | |
| Density | 1.206g/cm3 | Boiling Point | 257.1ºC at 760 mmHg | |
| Molecular Formula | C20H35NO3 | Melting Point | 194°C (lit.) | |
| MSDS | Chinese USA | Flash Point | 120.1ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Catalytic asymmetric construction of spiro(γ-butyrolactam-γ-butyrolactone) moieties through sequential reactions of cyclic imino esters with Morita-Baylis-Hillman bromides.
Chemistry 18(40) , 12614-8, (2012) Spiro(γ-butyrolactam-γ-butyrolactone): a route to enantioenriched spiro(γ-butyrolactam-γ-butyrolactone) compounds, a valuable motif for drug discovery, was developed by use of a highly efficient copper(I)/TF-BiphamPhos-catalyzed tandem Michael addition-elimin... |
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Characteristics of the Pseudomonas aeruginosa PA01 Intercellular Signaling Pathway (Quorum Sensing) Functioning in Presence of Porphyrins Bismuth Complexes.
Pol. J. Microbiol. 64 , 101-6, (2015) The influence of synthetic and natural porphyrins bismuth complexes on P. aeruginosa quorum sensing system was carried out by detection of the pyocyanin, rhamnolipids and autoinducers biosynthesis level. The highest ability to reduce pyocyanin biosynthesis sh... |
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Cell adhesion, ammonia removal and granulation of autotrophic nitrifying sludge facilitated by N-acyl-homoserine lactones.
Bioresour. Technol. 196 , 550-8, (2015) In this study, six N-acyl-homoserine lactone (AHL) molecules (C6-HSL, C8-HSL, C10-HSL, 3-oxo-C6-HSL, 3-oxo-C8-HSL and 3-oxo-C10-HSL) were each dosed into a bioreactor and seeded using autotrophic nitrifying sludge (ANS). The effects of the AHLs on cell adhesi... |
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[The influence of bacterial autoregulation molecules (homoserine lactones and alkyloxybenzoles) on oxidative metabolism of the natural immunity cellular effectors].
Mikrobiologiia 82(2) , 147-56, (2013)
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A bottom-up characterization of transfer functions for synthetic biology designs: lessons from enzymology.
Nucleic Acids Res. 42(22) , 14060-9, (2014) Within the field of synthetic biology, a rational design of genetic parts should include a causal understanding of their input-output responses-the so-called transfer function-and how to tune them. However, a commonly adopted strategy is to fit data to Hill-s... |
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Thapsigargin blocks Pseudomonas aeruginosa homoserine lactone-induced apoptosis in airway epithelia.
Am. J. Physiol. Cell Physiol. 306(9) , C844-55, (2014) Pseudomonas aeruginosa secretes N-(3-oxododecanoyl)-homoserine lactone (C12) as a quorum-sensing molecule to regulate gene expression. Micromolar concentrations are found in the airway surface liquid of infected lungs. Exposure of the airway surface to C12 ca... |
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Identification and characterization of a second quorum-sensing system in Agrobacterium tumefaciens A6.
J. Bacteriol. 196(7) , 1403-11, (2014) Quorum sensing (QS) is a widespread mechanism of bacterial communication in which individual cells produce and respond to small chemical signals. In Agrobacterium tumefaciens, an acylhomoserine lactone-dependent QS mechanism is known to regulate the replicati... |
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The bacterial quorum-sensing signal molecule N-3-oxo-dodecanoyl-L-homoserine lactone reciprocally modulates pro- and anti-inflammatory cytokines in activated macrophages.
J. Immunol. 191(1) , 337-44, (2013) The bacterial molecule N-3-oxo-dodecanoyl-l-homoserine lactone (C12) has critical roles in both interbacterial communication and interkingdom signaling. The ability of C12 to downregulate production of the key proinflammatory cytokine TNF-α in stimulated macr... |
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Effect of N-acy-l-homoserine lactones-like molecules from aerobic granules on biofilm formation by Escherichia coli K12.
Bioresour. Technol. 129 , 655-8, (2013) A laboratory study was conducted to investigate the production of quorum sensing (QS) molecules by aerobic granules in membrane-partitioned bioreactor. Flow-chamber (FC) tests with Escherichia coli K12 demonstrated that granules induced more attached growth o... |
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Design, synthesis and biological evaluation of N-sulfonyl homoserine lactone derivatives as inhibitors of quorum sensing in Chromobacterium violaceum.
Molecules 18(3) , 3266-78, (2013) A novel series of N-sulfonyl homoserine lactone derivatives 5a-l has been designed, synthesized and evaluated for quorum sensing inhibitory activities towards violacein production. Of the compounds synthesized, compound 5h was found to possess an excellent le... |