1,2,3,5-Tetrachlorobenzene

1,2,3,5-Tetrachlorobenzene Structure
1,2,3,5-Tetrachlorobenzene structure
Common Name 1,2,3,5-Tetrachlorobenzene
CAS Number 634-90-2 Molecular Weight 215.892
Density 1.6±0.1 g/cm3 Boiling Point 249.4±35.0 °C at 760 mmHg
Molecular Formula C6H2Cl4 Melting Point 54.5°C
MSDS Chinese USA Flash Point 110.0±23.3 °C
Symbol GHS06 GHS08
GHS06, GHS08
Signal Word Danger

QSPR modeling of octanol/water partition coefficient for vitamins by optimal descriptors calculated with SMILES.

Eur. J. Med. Chem. 43 , 714-40, (2008)

Simplified molecular input line entry system (SMILES) has been utilized in constructing quantitative structure-property relationships (QSPR) for octanol/water partition coefficient of vitamins and organic compounds of different classes by optimal descriptors....

Determination of chlorobenzenes in water samples by solid-phase disk extraction and gas chromatography-electron capture detection.

J. Chromatogr. Sci. 52(5) , 375-82, (2014)

A simple, rapid, sensitive and high throughput method is described, based on solid-phase disk extraction (SPDE) and gas chromatography-electron capture detection, for the determination of chlorobenzens (CBs) in water samples. The proposed SPDE sample pretreat...

Reductive dechlorination of hexachlorobenzene to tri- and dichlorobenzenes in anaerobic sewage sludge.

Appl. Environ. Microbiol. 54(2) , 327-30, (1988)

Hexachlorobenzene was dechlorinated to tri- and dichlorobenzenes in anaerobic sewage sludge. The complete biotransformation of 190 microM hexachlorobenzene (approximately 50 ppm) occurred within 3 weeks. The calculated rate of hexachlorobenzene dechlorination...

Bioconcentration of chlorinated anilines and benzene in fish: preliminary results.

Comp. Biochem. Physiol. C, Comp. Pharmacol. Toxicol. 100(1-2) , 55-7, (1991)

1. Seven chlorinated anilines and one chlorinated benzene were tested for their ability to bioconcentrate in guppies (Poecilia reticulata) under different experimental conditions. 2. Interactions between compounds in a mixture influence the bioconcentration o...

[The effect of some hexachlorobenzene catabolites on the porphyrin metabolism of rats (author's transl)].

Derm. Beruf Umwelt. 29(2) , 40-2, (1981)

In answering the question as to what role possible metabolites of hexachlorobenzene play in the procreation of toxic hexachlorobenzene porphyria in rats, both pure hexachlorobenzene and different mixtures were fed to them. In each case 20% of the hexachlorobe...

[Induction of micronuclei in polychromatic erythrocytes from mouse bone marrow following intraperitoneal administration of halogenated benzenes].

Boll. Soc. Ital. Biol. Sper. 66(7) , 709-16, (1990)

The mutagenicity of halogenated benzenes, including three isomers of tri- and tetrachlorobenzenes (TCB, TeCB) was studied on male Swiss CD1 mice by MN test. The data presented show that all the halogenated benzenes tested were found to be clastogenic apart fr...

A teratological evaluation and analysis of fetal tissue levels following administration of tetrachlorobenzene isomers to the rat.

Teratology 29(1) , 21-7, (1984)

Three tetrachlorobenzene (TCB) congeners (1,2,3,4- 1,2,3,5-, and 1,2,4,5-) were administered daily by gavage to pregnant Sprague-Dawley rats at levels of 50, 100, or 200 mg/kg from day 6 through day 15 of gestation. Mothers were sacrificed on day 21 of gestat...

Comparative toxicity of 1,2,3,4-, 1,2,4,5-, and 1,2,3,5-tetrachlorobenzene in the rat: results of acute and subacute studies.

J. Toxicol. Environ. Health A 11(4-6) , 663-77, (1983)

Groups of 10 male and 10 female rats were dosed orally with 1,2,3,4-, 1,2,4,5-, or 1,2,3,5-tetrachlorobenzene (TCB) at levels that ranged from 200 to 4000 mg/kg, and were observed clinically for 14 d. LD50 values for 1,2,3,4-, 1,2,4,5-, and 1,2,3,5-TCB were f...

Toxicokinetics of aromatic amines in guppy, Poecilia reticulata.

Sci. Total Environ. 109-110 , 383-6, (1991)

In this study the elimination kinetics of several chlorinated anilines and a tetrachlorobenzene in guppy, Poecilia reticulata, have been determined. The elimination of all the chlorinated anilines in fish showed a bi-phasic pattern, whereas the elimination ch...

Redox control and hydrogen production in sediment caps using carbon cloth electrodes.

Environ. Sci. Technol. 44(21) , 8209-15, (2010)

Sediment caps that degrade contaminants can improve their ability to contain contaminants relative to sand and sorbent-amended caps, but few methods to enhance contaminant degradation in sediment caps are available. The objective of this study was to determin...