Xylometazoline hydrochloride
Xylometazoline hydrochloride structure
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Common Name | Xylometazoline hydrochloride | ||
|---|---|---|---|---|
| CAS Number | 1218-35-5 | Molecular Weight | 280.836 | |
| Density | N/A | Boiling Point | 394.2ºC at 760 mmHg | |
| Molecular Formula | C16H25ClN2 | Melting Point | 131-133ºC | |
| MSDS | Chinese USA | Flash Point | 192.2ºC | |
| Symbol |
GHS06 |
Signal Word | Danger | |
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[Nasal decongestants and eye drops: keep out of children's reach!].
Perspect. Infirm. 10(2) , 63, (2013)
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Intranasal topical local anesthetic and decongestant for flexible nasendoscopy in children: a randomized, double-blind, placebo-controlled trial.
JAMA Otolaryngol. Head Neck Surg. 139(12) , 1301-5, (2013) To our knowledge, the present study is the first double-blind, randomized, placebo-controlled trial in children to compare nasal preparation sprays administered before flexible nasendoscopy with placebo.To compare the degree of pain experienced by children un... |
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Prognostic value of anterior rhinomanometry in diode laser turbinoplasty.
Arch. Otolaryngol. Head Neck Surg. 136(10) , 1015-9, (2010) To identify objective criteria predicting the success of diode laser-assisted turbinoplasty.Prospective before-and-after trial with follow-up of 8 weeks.Outpatient department of a tertiary referral center.Forty-one patients with nasal obstruction caused by hy... |
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Xylometazoline pretreatment reduces nasotracheal intubation-related epistaxis in paediatric dental surgery.
Br. J. Anaesth. 105(4) , 501-5, (2010) Epistaxis is the most common complication encountered during nasotracheal intubation (NTI) in children. The aim of this study was to test the efficacy of prophylactic intranasal admixture of xylometazoline and local anaesthetic gel in reducing epistaxis after... |
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Preparation of nose for nasal endoscopy: cotton pledget packing versus topical spray. A prospective randomized blinded study.
Eur. Arch. Otorhinolaryngol. 270(1) , 117-21, (2013) During nasal endoscopy it is essential to have proper visualization of structures with minimal discomfort to patient and surgeon. For this it is essential that the nose is well prepared before the procedure. The main objective of the study is to compare and e... |
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Nasal inspiratory flow: at rest and sniffing.
Int. Forum Allergy Rhinol. 1(2) , 128-35, (2011) This study quantifies the time-varying flow rate during inspiration at rest and in sniffing, both predecongestion and postdecongestion. It aims to provide a better understanding of nasal airflow mechanics, for application to the physiological modeling of nasa... |
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A comparative analysis of the decongestive effect of oxymetazoline and xylometazoline in healthy subjects.
Eur. J. Clin. Pharmacol. 67(1) , 19-23, (2011) Oxymetazoline and xylometazoline are locally effective and direct acting drugs that relieve nasal congestion. The aim of this study was to objectively determine and compare the decongestive effects of oxymetazoline and xylometazoline in healthy subjects.The s... |
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Alpha-adrenoceptor agonistic activity of oxymetazoline and xylometazoline.
Fundam. Clin. Pharmacol. 24(6) , 729-39, (2010) Oxymetazoline and xylometazoline are both used as nasal mucosa decongesting α-adrenoceptor agonists during a common cold. However, it is largely unknown which of the six α-adrenoceptor subtypes are actually present in human nasal mucosa, which are activated b... |
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Effects of topical drops and sprays on mucociliary transport time and nasal air flow.
Acta Otolaryngol. 129(11) , 1257-61, (2009) This study revealed that the nasal topical drops, which could be purchased without a proper prescription, should not be used randomly and non-selectively.To investigate the effect of nasal drops and sprays on the nasal air flow and mucociliary transport time ... |
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The evaluation of adenoid hypertrophy and obstruction grading based on rhinomanometry after nasal decongestant test in children.
Eur. Rev. Med. Pharmacol. Sci. 17(21) , 2962-7, (2013) Adenoid hypertrophy (AH) is a very common problem in children. Nasal Fiberoptic Endoscopy (NFE) represents the gold standard method to diagnose AH. Rhinomanometry represents a valid diagnostic support. The aim of our study was to analyze the grade of nasal ob... |