5-Bromopyridin-2-ol

5-Bromopyridin-2-ol Structure
5-Bromopyridin-2-ol structure
Common Name 5-Bromopyridin-2-ol
CAS Number 13466-38-1 Molecular Weight 174.00
Density 1.8±0.1 g/cm3 Boiling Point 322.8±22.0 °C at 760 mmHg
Molecular Formula C5H4BrNO Melting Point 180-183 °C(lit.)
MSDS Chinese USA Flash Point 149.0±22.3 °C
Symbol GHS07
GHS07
Signal Word Warning

Facile one-pot synthesis of N-difluoromethyl-2-pyridone derivatives.

Org. Lett. 8(17) , 3805-8, (2006)

[reaction: see text] A novel one-pot synthesis of N-difluoromethyl-2-pyridones is described. N-(Pyridin-2-yl)acetamide derivatives were excellent precursors for the preparation of N-difluoromethyl-2-pyridone derivatives. Difluoromethylation of 2-acetaminopyri...