Z-Ile-Glu-Thr-Asp-AFC

Z-Ile-Glu-Thr-Asp-AFC Structure
Z-Ile-Glu-Thr-Asp-AFC structure
Common Name Z-Ile-Glu-Thr-Asp-AFC
CAS Number 219138-02-0 Molecular Weight 821.75000
Density N/A Boiling Point N/A
Molecular Formula C37H42F3N5O13 Melting Point N/A
MSDS Chinese USA Flash Point N/A

A sequential two-step mechanism for the production of the mature p17:p12 form of caspase-3 in vitro.

J. Biol. Chem. 272 , 13432-13436, (1997)

The apoptotic cysteine protease, caspase-3, is expressed in cells as an inactive 32-kDa precursor from which 17 kDa (p17) and 12 kDa (p12) subunits of the mature caspase-3 are proteolytically generated during apoptosis. Two amino acid sequences, ESMD downward...