Dydrogesterone

Dydrogesterone Structure
Dydrogesterone structure
Common Name Dydrogesterone
CAS Number 152-62-5 Molecular Weight 312.446
Density 1.1±0.1 g/cm3 Boiling Point 462.8±45.0 °C at 760 mmHg
Molecular Formula C21H28O2 Melting Point 168-173°C
MSDS N/A Flash Point 172.2±25.7 °C

Coagulation and fibrynolitic parameters in women and the effects of hormone therapy; comparison of transdermal and oral administration.

Gynecol. Endocrinol. 29(2) , 165-8, (2013)

It is established that hormone therapy (HT) is related with significant increased prothrombotic risk factor. The aim of our study was to assess the effects of oral hormone therapy (o-HT) and transdermal hormone therapy (t-HT) on hemostasis parameters: fibrino...

Oral estradiol and dydrogesterone combination therapy in postmenopausal women: review of efficacy and safety.

Maturitas 76(1) , 10-21, (2013)

HRT is known to be effective for the relief of menopausal symptoms and prevention of osteoporosis. HRT should be tailored to the woman, enhancing the beneficial effects of the treatment while minimizing the risks. It is difficult to evaluate data on particula...

Hormone replacement therapy regimens in chemotherapy-induced premature ovarian failure and the subsequent correction of hormone levels.

Neuro Endocrinol. Lett. 33(7) , 697-702, (2012)

Premature ovarian failure (POF) is a consequence of gonadotoxic chemoradiotherapy given in antyneoplasia treatment. In young women it will correlate with menopausal symptoms which tend to appear due to depleted ovarian follicle reserve.It was a case series st...

Ovarian reserve markers and assisted reproductive technique (ART) outcomes in women with advanced endometriosis.

Reprod. Biol. Endocrinol. 12 , 120, (2014)

The role of ovarian reserve markers as predictors of the controlled ovarian stimulation (COS) response in intracytoplasmic sperm injection (ICSI) cycles in women with endometriosis has been much debated. The aim of the present study is to assess the predictab...

Double stimulations during the follicular and luteal phases of poor responders in IVF/ICSI programmes (Shanghai protocol).

Reprod. Biomed. Online 29(6) , 684-91, (2014)

Previous studies have shown that existing antral follicles in the luteal phase enable ovarian stimulation. In a pilot study, the efficacy of double stimulations during the follicular and luteal phases in women with poor ovarian response was explored (defined ...

A pilot study to search possible mechanisms of ultralong gonadotropin-releasing hormone agonist therapy in IVF-ET patients with endometriosis.

J. Ovarian Res. 7 , 100, (2015)

Additional treatment with a gonadotropin-releasing hormone (GnRH) agonist (GnRHa) before IVF-ET (ultralong GnRHa therapy) has been reported to improve the outcome of IVF-ET in endometriosis patients. However, the mechanism of ultralong GnRHa therapy is unclea...

Beneficial influence of postmenopausal estrogen therapy on serum adhesion molecules is independent of the route and dose of administration.

Neuro Endocrinol. Lett. 32(3) , 340-4, (2011)

In current literature, the immune-inflammatory theory of atherosclerosis is widely discussed. The role of how adhesion molecules contribute to the development of atheromatic plaques is especially underlined.120 females in menopausal age were included in the s...

Comparative effects of dydrogesterone and medroxyprogesterone acetate in critical areas: the brain and the vessels.

Gynecol. Endocrinol. 23 Suppl 1 , 9-16, (2007)

Several epidemiological and observational studies have investigated the role of hormone replacement therapy (HRT) in postmenopausal women. Within a few years, clinicians shifted from considering HRT as the panacea for everything to considering it a venomous p...

Successful use of dydrogesterone as maintenance therapy in recurrent endometrial stromal sarcoma: a case report.

Jpn. J. Clin. Oncol. 43(11) , 1145-9, (2013)

Endometrial stromal sarcoma is known to be a hormone-dependent tumor. Efficacy of hormonal therapy including high-dose progestins, aromatase inhibitors or gonadotropin-releasing hormone analogs has been reported. We report a case of recurrent endometrial stro...

Progestagens and anti-progestagens for pain associated with endometriosis.

Cochrane Database Syst. Rev. 3 , CD002122, (2012)

Endometriosis is a chronic inflammatory condition defined by the presence of glands and stroma outside the uterine cavity. It occurs in 7% to 10% of all women of reproductive age and may present as pain or infertility. The pelvic pain may be in the form of dy...