N,N-Dimethylacetamide

N,N-Dimethylacetamide Structure
N,N-Dimethylacetamide structure
Common Name N,N-Dimethylacetamide
CAS Number 127-19-5 Molecular Weight 87.120
Density 0.9±0.1 g/cm3 Boiling Point 166.1±0.0 °C at 760 mmHg
Molecular Formula C4H9NO Melting Point -20 °C
MSDS Chinese USA Flash Point 70.0±0.0 °C
Symbol GHS07 GHS08
GHS07, GHS08
Signal Word Danger

Accelerated hydrolysis of substituted cellulose for potential biofuel production: kinetic study and modeling.

Bioresour. Technol. 196 , 332-8, (2015)

In this work, kinetics of substitution accelerated cellulose hydrolysis with multiple reaction stages was investigated to lay foundation for mechanism study and molecular design of substituting compounds. High-efficiency hydrolysis of cellulose is critical fo...

Hemagglutinin-based polyanhydride nanovaccines against H5N1 influenza elicit protective virus neutralizing titers and cell-mediated immunity.

Int. J. Nanomedicine 10 , 229-43, (2015)

H5N1 avian influenza is a significant global concern with the potential to become the next pandemic threat. Recombinant subunit vaccines are an attractive alternative for pandemic vaccines compared to traditional vaccine technologies. In particular, polyanhyd...

A highly durable fuel cell electrocatalyst based on double-polymer-coated carbon nanotubes.

Sci. Rep. 5 , 16711, (2015)

Driven by the demand for the commercialization of fuel cell (FC) technology, we describe the design and fabrication of a highly durable FC electrocatalyst based on double-polymer-coated carbon nanotubes for use in polymer electrolyte membrane fuel cells. The ...

Polyanhydride Nanoparticle Delivery Platform Dramatically Enhances Killing of Filarial Worms.

PLoS Negl. Trop. Dis. 9 , e0004173, (2015)

Filarial diseases represent a significant social and economic burden to over 120 million people worldwide and are caused by endoparasites that require the presence of symbiotic bacteria of the genus Wolbachia for fertility and viability of the host parasite. ...

Remarkably regioselective deacylation of cellulose esters using tetraalkylammonium salts of the strongly basic hydroxide ion.

Carbohydr. Polym. 111 , 25-32, (2014)

Tetraalkylammonium hydroxides have been found to mediate regioselective deacylation of cellulose esters. This deacylation surprisingly shows substantial selectivity for the removal of the acyl groups at O-2/3, affording cellulose-6-O-esters by a simple, effic...

An Oligonucleotide Transfection Vector Based on HSA and PDMAEMA Conjugation: Effect of Polymer Molecular Weight on Cell Proliferation and on Multicellular Tumor Spheroids.

Macromol. Biosci. 15 , 965-78, (2015)

A novel gene transfection vector was fabricated based on the conjugation of human serum albumin (HSA) and maleimide end functionalized poly[(N,N-dimethylamino) ethyl methacrylate] (PDMAEMA). The bioconjugation was achieved in a site-specific manner to yield w...

Synthesis and In Vitro Evaluation of Thiolated Carrageenan.

J. Pharm. Sci. 104 , 2523-30, (2015)

The aim of this study was to generate and characterize a thiolated carrageenan. Thiolated carrageenan (carrageenan-SH) was synthesized from kappa (κ)- and iota (ι)-carrageenan by bromine replacement of the hydroxyl moieties followed by substitution to thiol g...

Removal of tetracycline from aqueous solution by a Fe3O4 incorporated PAN electrospun nanofiber mat.

J. Environ. Sci. (China) 28 , 29-36, (2015)

Pollution of antibiotics, a type of emerging contaminant, has become an issue of concern, due to their overuse in human and veterinary application, persistence in environment and great potential risk to human and animal health even at trace level. In this wor...

Development of polyether urethane intravaginal rings for the sustained delivery of hydroxychloroquine.

Drug Des. Devel. Ther. 8 , 1801-15, (2014)

Hydroxychloroquine (HCQ) has been shown to demonstrate anti-inflammatory properties and direct anti-HIV activity. In this study, we describe for the first time the fabrication and in vitro evaluation of two types of intravaginal ring (IVR) devices (a surfaced...

Design, synthesis and structure-activity relationship studies of novel and diverse cyclooxygenase-2 inhibitors as anti-inflammatory drugs.

J. Enzyme Inhib. Med. Chem. 29(6) , 846-67, (2014)

Because of the pivotal role of cyclooxygenase (COX) in the inflammatory processes, non-steroidal anti-inflammatory drugs (NSAIDs) that suppress COX activities have been used clinically for the treatment of inflammatory diseases/syndromes; however, traditional...