L-Tryptophanol
L-Tryptophanol structure
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Common Name | L-Tryptophanol | ||
|---|---|---|---|---|
| CAS Number | 2899-29-8 | Molecular Weight | 190.24200 | |
| Density | 1.245g/cm3 | Boiling Point | 444.2ºC at 760mmHg | |
| Molecular Formula | C11H14N2O | Melting Point | 73-77 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 222.5ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Enantioselective formal synthesis of (+)-dihydrocorynantheine and (-)-dihydrocorynantheol.
J. Org. Chem. 74(3) , 1205-11, (2009) The enantioselective construction of the 3-ethylindolo[2,3-a]quinolizidine moiety present in numerous indole alkaloids is reported, the key steps being a stereoselective cyclocondensation of (S)-tryptophanol with an appropriate racemic delta-oxoester and a re... |
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Straightforward methodology for the enantioselective synthesis of benzo[a]- and indolo[2,3-a]quinolizidines.
J. Org. Chem. 72(14) , 5193-201, (2007) An enantioselective two-step route to substituted benzo[a]- and indolo[2,3-a]quinolizidines has been developed. It consists of (i) a stereoselective cyclocondensation of a racemic or prochiral delta-oxo(di)ester with either (S)-(3,4-dimethoxyphenyl)alaninol o... |
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Enantioselective formal synthesis of ent-rhynchophylline and ent-isorhynchophylline.
Chem. Commun. (Camb.) 49(19) , 1954-6, (2013) Starting from (S)-tryptophanol, a formal synthesis of ent-rhynchophylline and ent-isorhynchophylline, involving stereoselective cyclocondensation, spirocyclization, and alkylation reactions, and the final adjustment of the oxidation level at the oxindole and ... |
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Tryptophanyl-tRNA synthetase in cell lines resistant to tryptophan analogs.
Exp. Cell Res. 195(1) , 66-78, (1991) Bovine kidney cell lines resistant to tryptamine and tryptophanol (tryptophan analogs) were selected. The content of tryptophanyl-tRNA synthetase (WRS, EC 6.1.1.2) was assayed by measuring the binding of monospecific polyclonal antibodies to the 35S-labeled e... |
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Lambda-carrageenan: a novel chiral selector for capillary electrophoresis.
Chirality 8(7) , 503-510, (1996) Lambda-carrageenan, a linear high molecular weight sulfated polysaccharide, has been employed as a chiral selector in capillary electrophoresis for the separation of enantiomers of weakly basic pharmaceutical compounds. The racemic compounds that were enantio... |
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Amino acid deprivation links BLIMP-1 to the immunomodulatory enzyme indoleamine 2,3-dioxygenase.
J. Immunol. 183(9) , 5768-77, (2009) Catabolism of tryptophan by IDO1 plays an important role in the control of immune responses. Activation of the eukaryotic initiation factor 2alpha (eIF2alpha) kinase general control nonderepressible-2 (GCN2) following tryptophan depletion is a major pathway m... |
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Quantifying prefibrillar amyloids in vitro by using a "thioflavin-like" spectroscopic method.
ChemBioChem. 11(13) , 1889-95, (2010) In Alzheimer's disease (AD) and other neurodegenerative disorders, proteins accumulate into ordered aggregates, called amyloids. Recent evidence suggests that these structures include both large, insoluble fibrils and smaller, prefibrillar structures, such as... |
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Direct high-performance liquid chromatographic separation of the enantiomers of an aromatic amine and four aminoalcohols using polysaccharide chiral stationary phases and acidic additive.
Chirality 19(8) , 647-53, (2007) The HPLC enantiomeric separation of N-benzyl-alpha-methyl-benzylamine, phenylalaninol, tryptophanol, 2 (diphenylhydroxymethyl)pyrrolidine, and isoproterenol was accomplished in the normal-phase mode using two polysaccharide-derived chiral stationary phases (C... |