Z-Phosphamidon

Z-Phosphamidon Structure
Z-Phosphamidon structure
Common Name Z-Phosphamidon
CAS Number 13171-21-6 Molecular Weight 299.688
Density 1.2±0.1 g/cm3 Boiling Point 356.0±42.0 °C at 760 mmHg
Molecular Formula C10H19ClNO5P Melting Point -45ºC
MSDS Chinese USA Flash Point 169.1±27.9 °C
Symbol GHS06 GHS08 GHS09
GHS06, GHS08, GHS09
Signal Word Danger

Purification and characterization of carboxylesterase from the seeds of Jatropha curcas.

Protein J. 31 , 120-128, (2012)

Carboxylesterases are hydrolases which catalyze the hydrolysis of various types of esters. Carboxylesterase from the seeds of Jatropha curcas has been purified to homogeneity using ammonium sulfate fractionation, CM-cellulose chromatography, Sephadex G-100 ch...

Acute poisoning with phosphamidon: determination of dimethyl phosphate (DMP) as a stable metabolite in a case of organophosphate insecticide intoxication.

J. Anal. Toxicol. 28(3) , 198-203, (2004)

Many organophosphate pesticides (OP) such as phosphamidon are unstable in aqueous solutions and especially in blood in the presence of esterases. In a case of intoxication, the phosphamidon concentration in serum decreased from 10 mg/L to 4.4 mg/L after stora...

Age-related differences in acute neurotoxicity produced by mevinphos, monocrotophos, dicrotophos, and phosphamidon.

Neurotoxicol. Teratol. 33(4) , 451-7, (2011)

Age-related differences in the acute neurotoxicity of cholinesterase (ChE)-inhibiting pesticides have been well-studied for a few organophosphates, but not for many others. In this study, we directly compared dose-responses using brain and red blood cell (RBC...

Delayed neuropathy and myelopathy after organophosphate intoxication.

N. Engl. J. Med. 347(14) , 1119-21, (2002)

Protective effect induced by atropine, carbamates, and 2-pyridine aldoxime methoiodide Artemia salina larvae exposed to fonofos and phosphamidon.

Ecotoxicol. Environ. Saf. 66(1) , 65-73, (2007)

The acute toxicity of fonofos and phosphamidon on three age classes of Artemia salina was evaluated. An increase in toxicity of these organophosphorous (OP) insecticides was found following longer development of A. salina. The effects of pretreatment with the...

Effect of phosphamidon on cognition and oxidative stress and its modulation by ascorbic acid and 4'-chlorodiazepam in rats.

Pharmacol. Biochem. Behav. 103(3) , 637-42, (2013)

Neurosteroids and micronutrient are known to possess neuromodulator and neuroprotective activities. The present study was designed to investigate the effect of 4'-chlorodiazepam (4CD) or ascorbic acid (Vit C) on phosphamidon (PM) induced modulation of cogniti...

Disseminated visceral coccidiosis in a wild white-naped crane (Grus vipio).

J. Wildl. Dis. 42(3) , 712-4, (2006)

Disseminated visceral coccidiosis (DVC) was unexpectedly recognized in a wild white-naped crane (Grus vipio) killed by phosphamidon insecticide. On gross pathologic examination, widely disseminated white nodules were found on the serosa of the pro-ventriculus...

Effect of phosphamidon on convulsive behavior and biochemical parameters: modulation by progesterone and 4'-chlorodiazepam in rats.

Naunyn Schmiedebergs Arch. Pharmacol. 382(4) , 311-20, (2010)

Phosphamidon (PHOS) has been shown to affect nervous system adversely. The present study was designed to explore the modulation of the effects of PHOS on convulsions by neurosteroids, progesterone (PROG), and 4'-chlorodiazepam (4'-CD), in both acute and chron...

Comparative study on individual and combined effects of dimecron and ziram on carbohydrate metabolites in liver, muscle, heart, and blood of a freshwater teleost, Sarotherodon mossambicus (Peters).

Bull. Environ. Contam. Toxicol. 72(2) , 365-72, (2004)

Effect of progesterone on phosphamidon-induced impairment of memory and oxidative stress in rats.

Hum. Exp. Toxicol. 30(10) , 1626-34, (2011)

Progesterone (a neurosteroid) is an important modulator of the nervous system functioning. Organophosphorus pesticides like phosphamidon have been shown to adversely affect memory and induce oxidative stress on both acute and chronic exposure. The present stu...