Cirsiliol
Cirsiliol structure
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Common Name | Cirsiliol | ||
|---|---|---|---|---|
| CAS Number | 34334-69-5 | Molecular Weight | 330.289 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | 616.1±55.0 °C at 760 mmHg | |
| Molecular Formula | C17H14O7 | Melting Point | 280-281.5℃ (methanol ) | |
| MSDS | Chinese USA | Flash Point | 230.8±25.0 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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[Chemical constituents of Eupatorium lindleyanum].
Zhongguo Zhong Yao Za Zhi 37(7) , 937-40, (2012) To study chemical constituents of Eupatorium lindleyanum. Ethyl acetate extractive fractions were separated with silica gel and Sephadex LH-20 by column chromatography, and their structures were identified on the basis of spectroscopic analysis and chemical e... |
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[Determination of flavonoids in buds of Herba Artemisiae Scopariae by HPLC].
Zhongguo Zhong Yao Za Zhi 30(8) , 591-4, (2005) To develop a quantitative method for the determination of four flavonoids in buds of Herba Artemisiae Scopariae.The sample was extracted by ultrasonic with ethyl acetate for 30 minutes and separated on kromasil ODS column with mobile phase of acetonitrile-tet... |
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Potent and selective 5-lipoxygenase inhibitors: cirsiliol and AA-861.
Adv. Prostaglandin. Thromboxane. Leukot. Res. 15 , 217-9, (1985)
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[Studies on chemical constituents in buds of Artemisia scoparia].
Zhongguo Zhong Yao Za Zhi 27(3) , 202-4, (2002) To investigate the chemical constituents in flower buds of Artemisia scoparia.The constituents were separated and purified by means of various chromatographic techniques, and their structures were determined on the basis of physical and chemical properties an... |
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GABA(A)-receptor ligands of flavonoid structure.
Curr. Top. Med. Chem 2(8) , 853-67, (2002) This review describes the new research developments that have established the CNS-activity of some natural flavonoids. The properties of flavone, chrysin, apigenin and cirsiliol are described and a survey of the occurrence of ligands for the benzodiazepine bi... |
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Arachidonate 5-lipoxygenase and its new inhibitors.
J. Allergy Clin. Immunol. 74(3 Pt 2) , 349-52, (1984) The 5-lipoxygenases of guinea pig peritoneal polymorphonuclear leukocytes and of rat basophilic leukemia cells have been solubilized, purified partially by affinity chromatography, and shown to convert arachidonic acid principally to 5-hydroperoxy-6,8,11,14- ... |
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Growth inhibition of human malignant glioma cells in vitro by agents which interfere with biosynthesis of eicosanoids.
Anticancer Res. 12(3) , 981-6, (1992) In an attempt to find new methods for the treatment of malignant gliomas a number of tests have been performed to learn whether growth of such cells in vitro may be affected by agents which interfere with the biosynthesis of eicosanoids. It was observed that ... |
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Syntheses of 5,6,7- and 5,7,8-trioxygenated 3',4'-dihydroxyflavones having alkoxy groups and their inhibitory activities against arachidonate 5-lipoxygenase.
J. Med. Chem. 29(11) , 2256-62, (1986) Arachidonate 5-lipoxygenase plays a pivotal role in the biosynthesis of leukotrienes. Cirsiliol (3',4',5-trihydroxy-6,7-dimethoxyflavone), a selective inhibitor of the enzyme, was derivatized by introducing alkyl groups of various chain lengths at positions 5... |
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Effects of cirsiliol, a flavone isolated from Achillea fragrantissima, on rat isolated ileum.
Gen. Pharmacol. 23(3) , 555-60, (1992) 1. In concentrations from 10(-8) M to 3 x 10(-4) M, cirsiliol caused concentration-dependent relaxation of rat isolated ileum. 2. Phentolamine (10(-6) M) or phentolamine and propranolol (10(-6) M) had no significant effects on the concentration-effect curves ... |
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Flavonoids: potent inhibitors of arachidonate 5-lipoxygenase.
Biochem. Biophys. Res. Commun. 116(2) , 612-8, (1983) Various flavonoids were found to be relatively selective inhibitors of arachidonate 5-lipoxygenase which initiates the biosynthesis of leukotrienes with the activity of slow reacting substance of anaphylaxis. Cirsiliol (3',4',5-trihydroxy-6,7-dimethoxyflavone... |