Ceric ammonium nitrate (CAN) promoted efficient solid phase synthesis of amide derivatives: A green approach

CS Reddy, M Raghu, A Nagaraj

Index: Reddy, Ch. Sanjeeva; Raghu; Nagaraj Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2008 , vol. 47, # 2 p. 315 - 318

Full Text: HTML

Citation Number: 9

Abstract

Abstract: Ceric ammonium nitrate (CAN) has been found to be an efficient catalyst for the solid phase synthesis of amide derivatives of a wide range of substituted carboxylic acids and urea in excellent yields under microwave irradiation conditions. High yields are achieved even on a gram scale, while reaction times are considerably shortened. This method displays both economic and environmental advantages.

~90%

~82%

~89%

~89%

~93%

~84%

~85%

~88%

3H-1, 2, 4-Dithiazol-3-one compounds as novel potential affo...

[Bioorganic and Medicinal Chemistry Letters, , vol. 23, # 5 p. 1424 - 1427]

Synthesis of 2-amidopyrazine

[Kagarlitskii, A. D.; Krichevskii, L. A.; Suvorov, B. V. Pharmaceutical Chemistry Journal, 1993 , vol. 27, # 3 p. 219 - 220 Khimiko-Farmatsevticheskii Zhurnal, 1993 , vol. 27, # 3 p. 45 - 47]

Catalytic synthesis of pyrazinamide from 2, 5-dimethylpyrazi...

[Pharmaceutical Chemistry Journal, , vol. 33, # 7 p. 381 - 383]

Polar effects in free-radical reactions. New synthetic devel...

[Minisci, Francesco; Citterio, Attilio; Vismara, Elena; Giordano, Claudio Tetrahedron, 1985 , vol. 41, # 19 p. 4157 - 4170]

Catalytic synthesis of pyrazinamide from 2, 5-dimethylpyrazi...

[Pharmaceutical Chemistry Journal, , vol. 33, # 7 p. 381 - 383]