Chemoselective protection of carboxylic acid as methyl ester: A practical alternative to diazomethane protocol

AK Chakraborti, A Basak, V Grover

Index: Chakraborti, Asit K.; Basak, Anindita; Grover, Vikas Journal of Organic Chemistry, 1999 , vol. 64, # 21 p. 8014 - 8017

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Citation Number: 98

Abstract

Functional group protection is an indispensable artifice employed to prevent or to modify the reaction of a specific functional group during a synthetic sequence. Development of newer methods for protection/deprotection of functional groups constitutes a topic of constant interest. 1 In this context carboxylic acid protection is an important transformation and is frequently achieved via methyl ester formation2 because of ease of deprotection. 1, 3 ...

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