Synlett

α, α-diacetyl cyclic ketene dithioacetals: Odorless and efficient dithiol equivalents in thioacetalization reactions

H Yu, Q Liu, Y Yin, Q Fang, J Zhang, D Dong

Index: Yu, Haifeng; Liu, Qun; Yin, Yanbing; Fang, Qunxin; Zhang, Jingping; Dong, Dewen Synlett, 2004 , # 6 p. 999 - 1002

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Citation Number: 35

Abstract

Abstract Two novel, non-thiolic, odorless dithiol equivalents, α, α-diacetyl cyclic ketene dithioacetals 2a and 2b, had been developed. A range of carbonyl compounds 3 were converted into corresponding dithioacetals, dithianes 4 and dithiolanes 5, in high yields (up to 99%) in the presence of 2a or 2b. Moreover, 2a and 2b show high chemoselectivity between aldehyde and ketone in thioacetalization.