Selective Arylation and Vinylation at the α Position of Vinylarenes

…, L Qin, X Ren, Y Lu, Y Li, JS Zhou

Index: Zou, Yinjun; Qin, Liena; Ren, Xinfeng; Lu, Yunpeng; Li, Yongxin; Zhou, Jianrong Chemistry - A European Journal, 2013 , vol. 19, # 10 p. 3504 - 3511

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Citation Number: 12

Abstract

Abstract In intermolecular Heck reactions of styrene and vinylarenes, the aryl and vinyl groups routinely insert at the β position. However, selective insertion at the α position has been very rare. Herein, we provide a missing piece in the palette of Heck reaction, which gave> 20: 1 α selectivity. The key to our success is a new ferrocene 1, 1′-bisphosphane (dnpf) that carries 1-naphthyl groups. Our mechanistic studies revealed that the high α ...

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