Zinc tetrafluoroborate hydrate as a mild catalyst for epoxide ring opening with amines: scope and limitations of metal tetrafluoroborates and applications in the …

B Pujala, S Rana, AK Chakraborti

Index: Pujala, Brahmam; Rana, Shivani; Chakraborti, Asit K. Journal of Organic Chemistry, 2011 , vol. 76, # 21 p. 8768 - 8780

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Citation Number: 50

Abstract

The scope and limitations of metal tetrafluoroborates have been studied for epoxide ring- opening reaction with amines, and Zn (BF4) 2· x H2O has been found to be a mild and efficient catalyst affording high yields under solvent-free conditions at rt with excellent chemo- , regio-, and stereoselectivities. The catalytic efficiency followed the order Zn (BF4) 2· x H2O≫ Cu (BF4) 2· x H2O> Co (BF4) 2· 6H2O≫ Fe (BF4) 2· 6H2O> LiBF4 for reactions ...