Mercury in organic chemistry. 26. Synthesis of heterocycles via intramolecular solvomercuration of aryl acetylenes

RC Larock, LW Harrison

Index: Larock, Richard C.; Harrison, L. Wayne Journal of the American Chemical Society, 1984 , vol. 106, # 15 p. 4218 - 4227

Full Text: HTML

Citation Number: 133

Abstract

Abstract: A number of ortho substituted aryl acetylenes, o-CH3XC6H4YC= CR (X= 0, S, CO,; Y=-, CO), have been observed to undergo facile intramolecular solvomercuration with mercuric acetate in acetic acid to afford the corresponding benzofuran, benzothiophene, isocoumarin, and chromone organomercuric chlorides, after aqueous sodium chloride workup. The aryl acetylenes m-XC6H4YCH2C== CR (X= H, Y= 0, R= CH,; X= CH30, Y= ...