Tetrahedron Letters

A mild and selective method for the cleavage of tert-butyl esters

RW Jackson

Index: Jackson, Randy W Tetrahedron Letters, 2001 , vol. 42, # 31 p. 5163 - 5165

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Citation Number: 36

Abstract

Acid labile protecting groups play an important role in organic synthesis. Among them, tert-butyl esters are commonly employed in the synthesis of peptides, alkaloids and other natural products and substrates of medicinal interest. 1., and Removal of t-butyl esters often involves the use of