Suzuki–Miyaura Cross??Coupling under Solvent??Free Conditions

AF Asachenko, KR Sorochkina…

Index: Asachenko, Andrey F.; Sorochkina, Kristina R.; Dzhevakov, Pavel B.; Topchiy, Maxim A.; Nechaev, Mikhail S. Advanced Synthesis and Catalysis, 2013 , vol. 355, # 18 p. 3553 - 3557

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Citation Number: 5

Abstract

Abstract: A solvent-free reaction protocol for Suzuki–Miyaura cross-couplings was developed.(Hetero) aryl bromides and chlorides are coupled with pinacol arylboronates in high yields. The reaction is catalyzed by conventional bis (triphenylphosphine) palladium (II) chloride [(PPh3) 2PdCl2] and/or palladium (II) acetate/SPhos[PdACHTUNGTRENNUNG (OAc) 2/SPhos] under air. Keywords: carbenes; palladium; phosphanes; solvent-free ...

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