Tetrahedron letters

Environmentally benign oxidation reaction of aldehydes to their corresponding carboxylic acids using Pd/C with NaBH 4 and KOH

M Lim, CM Yoon, G An, H Rhee

Index: Lim, Minkyung; Yoon, Cheol Min; An, Gwangil; Rhee, Hakjune Tetrahedron Letters, 2007 , vol. 48, # 22 p. 3835 - 3839

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Citation Number: 33

Abstract

Pd/C catalyst in aqueous methanol with sodium borohydride and potassium hydroxide under the air efficiently oxidized aldehydes to their corresponding carboxylic acids at room temperature. The utilization of room temperature reaction, aqueous methanol solvent, and the open-air conditions make this manipulation very interesting for economic and environmental perspectives.