7-Hydroxycoumarine

Modify Date: 2025-08-23 07:37:10

7-Hydroxycoumarine Structure
7-Hydroxycoumarine structure
Common Name 7-Hydroxycoumarine
CAS Number 93-35-6 Molecular Weight 162.142
Density 1.4±0.1 g/cm3 Boiling Point 382.1±37.0 °C at 760 mmHg
Molecular Formula C9H6O3 Melting Point 230 °C (dec.)(lit.)
MSDS Chinese USA Flash Point 181.2±19.3 °C
Symbol GHS07
GHS07
Signal Word Warning

 Use of 7-Hydroxycoumarine


Umbelliferone, a natural product of the coumarin family, is a fluorescing compound which can be used as a sunscreen agent.

 Names

Name umbelliferone
Synonym More Synonyms

 7-Hydroxycoumarine Biological Activity

Description Umbelliferone, a natural product of the coumarin family, is a fluorescing compound which can be used as a sunscreen agent.
Related Catalog
Target

Human Endogenous Metabolite

References

[1]. Yu SM, et al. Umbelliferone exhibits anticancer activity via the induction of apoptosis and cell cycle arrest in HepG2 hepatocellular carcinoma cells. Mol Med Rep. 2015 Sep;12(3):3869-3873.

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 382.1±37.0 °C at 760 mmHg
Melting Point 230 °C (dec.)(lit.)
Molecular Formula C9H6O3
Molecular Weight 162.142
Flash Point 181.2±19.3 °C
Exact Mass 162.031693
PSA 50.44000
LogP 1.58
Vapour Pressure 0.0±0.9 mmHg at 25°C
Index of Refraction 1.640
InChIKey ORHBXUUXSCNDEV-UHFFFAOYSA-N
SMILES O=c1ccc2ccc(O)cc2o1
Storage condition -20°C Freezer
Water Solubility 1 g/100 mL (100 ºC)

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
GN6820000
CHEMICAL NAME :
Coumarin, 7-hydroxy-
CAS REGISTRY NUMBER :
93-35-6
BEILSTEIN REFERENCE NO. :
0127683
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C9-H6-O3
MOLECULAR WEIGHT :
162.15
WISWESSER LINE NOTATION :
T66 BOVJ IQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
450 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :
Mutation in microorganisms
TEST SYSTEM :
Bacteria - Klebsiella pneumoniae
DOSE/DURATION :
800 mg/L
REFERENCE :
JIMMBG Journal of Immunological Methods. (Elsevier Science Pub. Co., Inc., 52 Vanderbilt Ave., New York, NY 10017) V.1- 1971- Volume(issue)/page/year: 36,55,1980

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi:Irritant;
Risk Phrases R36/37/38
Safety Phrases S26-S36
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS GN6820000
HS Code 29322980

 Synthetic Route

 Customs

HS Code 2932209090
Summary 2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles104

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 Synonyms

UMBELLIFERON
Hydrangine
Umbelliferone
Hydramgin
7-Hydroxy-2H-chromen-2-one
Dichrin A
7-hydroxy-2H-1-benzopyran-2-one
EINECS 202-240-3
Skimmetine
umberlliferone
SKIMMETIN
7-Hydroxycoumarin
7-hydroxy-coumarin
7-hydroxy-coumarine
MFCD01861511
hydrangin
7 HC
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