124753-97-5

124753-97-5 structure

Name: N-(hexanoyl)sphing-4-enine
Chemical Name: 6-Hexanoyl-D-erythro-sphingosine
CAS Number: 124753-97-5
Molecular Formula: C₂₄H₄₇NO₃
Molecular Weight: 397.63
Catalog: Signaling Pathways Apoptosis Apoptosis
Create Date: 2018-08-08 20:33:47
Modify Date: 2024-01-11 18:56:12
C6-ceramide, a ceramide pathway activator, shows activity against a variety of cancer cell lines. C6-ceramide can be used as an adjuvant for chemotherapeutic agents, to enhance anti-tumor effects[1][2].

Name	6-Hexanoyl-D-erythro-sphingosine
Synonyms	N-Hexanoyl-D-sphingosine N-hexanoyl-D-erythro-sphingosine C6 ceramide Caproyl ceramide N-Caproyl-D-sphingosine N-(hexanoyl)sphing-4-enine N-(hexanoyl)-sphing-4-enine Hexanamide, N-[(1S,2R,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]- MFCD00870174 N-[(2S,3R,4E)-1,3-Dihydroxy-4-octadecen-2-yl]hexanamide

Description	C6-ceramide, a ceramide pathway activator, shows activity against a variety of cancer cell lines. C6-ceramide can be used as an adjuvant for chemotherapeutic agents, to enhance anti-tumor effects[1][2].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer
References	[1]. Zhu Q, et, al. C6-ceramide synergistically potentiates the anti-tumor effects of histone deacetylase inhibitors via AKT dephosphorylation and α-tubulin hyperacetylation both in vitro and in vivo. Cell Death Dis. 2011 Jan 27;2(1):e117. [2]. Liu L, et, al. C6-ceramide treatment inhibits the proangiogenic activity of multiple myeloma exosomes via the miR-29b/Akt pathway. J Transl Med. 2020 Aug 3;18(1):298.

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Safety Phrases	S22-S24/25
RIDADR	NONH for all modes of transport