312747-21-0
312747-21-0 structure
- Name: HUP30
- Chemical Name: N-(6-nitro-1,3-benzothiazol-2-yl)cyclohexanecarboxamide
- CAS Number: 312747-21-0
- Molecular Formula: C14H15N3O3S
- Molecular Weight: 305.35200
- Catalog: Signaling Pathways Membrane Transporter/Ion Channel Calcium Channel
- Create Date: 2016-12-11 16:48:00
- Modify Date: 2024-01-10 15:02:28
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HUP30 is a vasodilating agent. HUP30 stimulates soluble guanylyl cyclase, activate K+ channels, and blocks extracellular Ca2+ influx[1].
| Name | N-(6-nitro-1,3-benzothiazol-2-yl)cyclohexanecarboxamide |
|---|---|
| Synonyms | f0327-0054 |
| Description | HUP30 is a vasodilating agent. HUP30 stimulates soluble guanylyl cyclase, activate K+ channels, and blocks extracellular Ca2+ influx[1]. |
|---|---|
| Related Catalog | |
| In Vitro | HUP30 抑制苯肾上腺素诱导的主动脉收缩，IC50 值为 3.9 μM[1]。 HUP30 (100 μM) 增加去氧肾上腺素刺激的主动脉中的 cGMP 水平[1]。 HUP30 对 25/30 mM K+ 收缩的大鼠主动脉环产生解痉作用，IC50 值为 7.5 μM[1] . HUP30 (3-100 μM) 抑制苯肾上腺素诱导的细胞外 Ca2+ 内流和 Ca2+ 动员[1]。 HUP30 (10-100 μM) 抑制单尾动脉肌细胞中的电流[1]。 |
| References |
| Molecular Formula | C14H15N3O3S |
|---|---|
| Molecular Weight | 305.35200 |
| Exact Mass | 305.08300 |
| PSA | 119.54000 |
| LogP | 4.89600 |
