Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: UNII:H1547KG7UZ
Price: ￥108.0/5g ￥348.0/25g
Purity: 99.0%
Stocking Period: 2 Day
Contact: Liu jia

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 2-Methylsuccinic acid
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

498-21-5

498-21-5 structure

498-21-5 structure

Name: UNII:H1547KG7UZ
Chemical Name: 2-Methylsuccinic acid
CAS Number: 498-21-5
Molecular Formula: C₅H₈O₄
Molecular Weight: 132.115
Catalog: Chemical reagent Organic reagent Aromatic acid
Create Date: 2018-06-21 11:50:27
Modify Date: 2024-01-10 09:44:20
2-Methylsuccinic acid is a normal metabolite in human fluids and the main biochemical measurable features in ethylmalonic encephalopathy.

Name	2-Methylsuccinic acid
Synonyms	UNII:H1547KG7UZ d-Methylsuccinic acid 2-methylbutanedioic acid 2-Methylsuccinic acid Pyrotartaric Acid METHYLSUCCINIC ACID MFCD00002659 Butanedioic acid, 2-methyl- EINECS 207-857-1 Methylbutanedioic acid

Description	2-Methylsuccinic acid is a normal metabolite in human fluids and the main biochemical measurable features in ethylmalonic encephalopathy.
Related Catalog	Natural Products >> Acids and Aldehydes Research Areas >> Metabolic Disease
Target	Human Endogenous Metabolite
In Vitro	2-Methylsuccinic acid is a normal metabolite in human fluids and the main biochemical measurable features in ethylmalonic encephalopathy[1]. The underlying biochemical defect involves isoleucine catabolism[2].
References	[1]. Grosso S, et al. Ethylmalonic encephalopathy: further clinical and neuroradiological characterization. J Neurol. 2002 Oct;249(10):1446-50. [2]. Nowaczyk MJ, et al. Ethylmalonic and methylsuccinic aciduria in ethylmalonic encephalopathy arise from abnormal isoleucine metabolism. Metabolism. 1998 Jul;47(7):836-9.

Density	1.3±0.1 g/cm3
Boiling Point	236.5±13.0 °C at 760 mmHg
Melting Point	110-115 °C(lit.)
Molecular Formula	C₅H₈O₄
Molecular Weight	132.115
Flash Point	111.1±16.3 °C
Exact Mass	132.042252
PSA	74.60000
LogP	-0.24
Vapour Pressure	0.0±1.0 mmHg at 25°C
Index of Refraction	1.474
Stability	Stable. Combustible. Incompatible with bases, oxidizing agents, reducing agents.

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xi:Irritant
Risk Phrases	R36/37/38
Safety Phrases	S26-S36
RIDADR	NONH for all modes of transport
WGK Germany	3
HS Code	2917190090

Precursor 9
498-23-7 97-65-4 4457-71-0 617-52-7
7338-27-4 1679-47-6 498-24-8 127-17-3
87-69-4
DownStream 9
3641-51-8 4100-80-5 7732-18-5 498-24-8
22644-27-5 78-75-1 616-44-4 71-23-8
187737-37-7

HS Code	2917190090
Summary	2917190090 acyclic polycarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%