101910-24-1
101910-24-1 structure
- Name: L-655238
- Chemical Name: 1-[3-(quinolin-2-ylmethoxy)phenyl]hexan-1-ol
- CAS Number: 101910-24-1
- Molecular Formula: C22H25NO2
- Molecular Weight: 335.439
- Create Date: 2017-06-30 10:33:05
- Modify Date: 2024-01-10 12:17:04
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REV 5901 is a competitive and orally active antagonist of leukotriene receptor, with a Ki of 0.7 μM. REV 5901 is also a 5-lipoxygenase inhibitor. REV 5901 can be used for the research of asthma in which leukotriene release be involved[1][2].
| Name | 1-[3-(quinolin-2-ylmethoxy)phenyl]hexan-1-ol |
|---|---|
| Synonyms |
rev-5901
rg 5901 Benzenemethanol, α-pentyl-3-(2-quinolinylmethoxy)- 1-[3-(2-Quinolinylmethoxy)phenyl]-1-hexanol pf 5901 1-[3-(Quinolin-2-ylmethoxy)phenyl]hexan-1-ol |
| Description | REV 5901 is a competitive and orally active antagonist of leukotriene receptor, with a Ki of 0.7 μM. REV 5901 is also a 5-lipoxygenase inhibitor. REV 5901 can be used for the research of asthma in which leukotriene release be involved[1][2]. |
|---|---|
| Related Catalog | |
| Target |
Ki: 0.7 μM (leukotriene receptor)[1] [2] |
| References |
| Density | 1.1±0.1 g/cm3 |
|---|---|
| Boiling Point | 497.7±35.0 °C at 760 mmHg |
| Molecular Formula | C22H25NO2 |
| Molecular Weight | 335.439 |
| Flash Point | 254.8±25.9 °C |
| Exact Mass | 335.188538 |
| PSA | 42.35000 |
| LogP | 4.94 |
| Vapour Pressure | 0.0±1.3 mmHg at 25°C |
| Index of Refraction | 1.606 |
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xi |
| Risk Phrases | R36/37/38 |
| Safety Phrases | 26-36 |
| RIDADR | NONH for all modes of transport |
|
~85%
101910-24-1 |
| Literature: White; Yager; Stappenbeck Journal of Organic Chemistry, 1993 , vol. 58, # 12 p. 3466 - 3468 |
|
~%
101910-24-1 |
| Literature: White; Yager; Stappenbeck Journal of Organic Chemistry, 1993 , vol. 58, # 12 p. 3466 - 3468 |
|
~%
101910-24-1 |
| Literature: White; Yager; Stappenbeck Journal of Organic Chemistry, 1993 , vol. 58, # 12 p. 3466 - 3468 |
|
~%
101910-24-1 |
| Literature: Musser; Chakraborty; Sciortino; Gordon; Khandwala; Neiss; Pruss; Van Inwegen; Weinryb; Coutts Journal of Medicinal Chemistry, 1987 , vol. 30, # 1 p. 96 - 104 |
|
~%
101910-24-1 |
| Literature: Musser; Chakraborty; Sciortino; Gordon; Khandwala; Neiss; Pruss; Van Inwegen; Weinryb; Coutts Journal of Medicinal Chemistry, 1987 , vol. 30, # 1 p. 96 - 104 |
|
~%
101910-24-1 |
| Literature: Musser; Chakraborty; Sciortino; Gordon; Khandwala; Neiss; Pruss; Van Inwegen; Weinryb; Coutts Journal of Medicinal Chemistry, 1987 , vol. 30, # 1 p. 96 - 104 |
|
~%
101910-24-1 |
| Literature: White; Yager; Stappenbeck Journal of Organic Chemistry, 1993 , vol. 58, # 12 p. 3466 - 3468 |
|
~%
101910-24-1 |
| Literature: White; Yager; Stappenbeck Journal of Organic Chemistry, 1993 , vol. 58, # 12 p. 3466 - 3468 |
