Shanghai Nianxing Industrial Co., Ltd
China
Product Name: AG 556
Price: Check
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: (E)-AG 556
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: TYRPHOSTIN B56
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

Shanghai Amole Biotechnology Co., Ltd.
China
Product Name: AG 556
Price: ￥Inquiry/100mg ￥Inquiry/1g ￥Inquiry/250mg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Xiyao Wang
Email: 3623107365@qq.com

133550-41-1

133550-41-1 structure

133550-41-1 structure

Name: AG 556
Chemical Name: (E)-2-Cyano-3-(3,4-dihydroxyphenyl)-N-(4-phenylbutyl)-2-propenamide
CAS Number: 133550-41-1
Molecular Formula: C₂₀H₂₀N₂O₃
Molecular Weight: 336.38400
Create Date: 2018-08-02 10:39:57
Modify Date: 2025-08-26 16:25:37
(E)-AG 556 is a highly selective EGFR inhibitor and also blocks LPS-induced TNF-α production[1][2].

Name	(E)-2-Cyano-3-(3,4-dihydroxyphenyl)-N-(4-phenylbutyl)-2-propenamide
Synonyms	Tyrphostin B 56 AG 556 TYRPHOSTIN AG 556

Description	(E)-AG 556 is a highly selective EGFR inhibitor and also blocks LPS-induced TNF-α production[1][2].
Related Catalog	Signaling Pathways >> JAK/STAT Signaling >> EGFR Signaling Pathways >> Protein Tyrosine Kinase/RTK >> EGFR Research Areas >> Inflammation/Immunology
References	[1]. Gazit A, et al. Tyrphostins. 2. Heterocyclic and alpha-substituted benzylidenemalononitrile tyrphostins as potent inhibitors of EGF receptor and ErbB2/neu tyrosine kinases. J Med Chem. 1991 Jun;34(6):1896-907. [2]. George J, et al. Tyrphostin AG-556 reduces myocardial infarct size and improves cardiac performance in the rat. Exp Mol Pathol. 2003 Jun;74(3):314-8.

Density	1.247g/cm3
Boiling Point	636.1ºC at 760mmHg
Molecular Formula	C₂₀H₂₀N₂O₃
Molecular Weight	336.38400
Flash Point	338.5ºC
Exact Mass	336.14700
PSA	93.35000
LogP	3.53478
Vapour Pressure	8.95E-17mmHg at 25°C
Index of Refraction	1.638
Storage condition	-20°C

Safety Phrases	S22-S24/25

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